Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 9/20 | 0.62 |
| ▸ | TTBK2 | Q6IQ55 | 9/20 | 0.62 |
| ▸ | BTK | Q06187 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409027 | 0.86 | TTBK1 (0.62) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL16266363 | 0.85 | TTBK1 (0.61) | TTBK1TTBK2BTKHDAC6 | |
| SCHEMBL23409028 | 0.83 | TTBK1 (0.59) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL8469366 | 0.81 | S1PR2 (0.57) | TTBK1TTBK2BTKHDAC6 | |
| SCHEMBL16266488 | 0.81 | LDHA (0.58) | TTBK1TTBK2BTKHDAC6 | |
| SCHEMBL24920137 | 0.81 | TTBK1 (0.57) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL23409023 | 0.81 | GAA (0.57) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL4741877 | 0.81 | TTBK1 (0.76) | TTBK1TTBK2BTKHDAC6EGFR | |
| SCHEMBL11828413 | 0.80 | S1PR2 (0.59) | TTBK1TTBK2BTKHDAC6HPGDS | |
| SCHEMBL25069022 | 0.80 | TTBK1 (0.56) | TTBK1TTBK2BTKHDAC6HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606929-B | Preparation method of Degatinib | 中瀚(齐河县)生物医药科技有限公司 | 2023-07-07 | — | — | CN | disclosed |