Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.72 |
| ▸ | CDK9 | P50750 | 4/20 | 0.69 |
| ▸ | CCNK | O75909 | 3/20 | 0.69 |
| ▸ | CCND3 | P30281 | 3/20 | 0.69 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.69 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.69 |
| ▸ | CDK2 | P24941 | 2/20 | 0.69 |
| ▸ | BRD4 | O60885 | 12/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.61 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.61 |
| ▸ | PAK4 | O96013 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | CSF1R | P07333 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331219 | 0.88 | ALK (0.74) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL23704663 | 0.88 | ALK (0.74) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL25068892 | 0.84 | ALK (0.68) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL25068891 | 0.84 | ALK (0.68) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL20444236 | 0.83 | ALK (0.73) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL30463630 | 0.82 | ALK (0.65) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL21637841 | 0.82 | CDK2 (0.67) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL25068846 | 0.82 | CDK9 (0.82) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL29037749 | 0.82 | ALK (0.69) | ALKCDK9CCNKCCND3CDK6 | |
| SCHEMBL23409097 | 0.82 | CCNA2 (1.00) | ALKCDK9CCNKCCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021099842-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO INC. (CA) | 2021-05-27 | — | — | WO | disclosed |