⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005 | 0.73 | SPHK1 (0.45) | — | |
| SCHEMBL4204710 | 0.72 | SPHK1 (0.48) | — | |
| SCHEMBL4204837 | 0.72 | SPHK1 (0.48) | — | |
| SCHEMBL28869453 | 0.72 | SPHK1 (0.48) | — | |
| SCHEMBL5172111 | 0.71 | PTGS1 (0.39) | — | |
| SCHEMBL3817338 | 0.71 | LMNA (0.45) | — | |
| SCHEMBL4967318 | 0.70 | TRPV1 (0.38) | — | |
| SCHEMBL11126683 | 0.70 | TRPV1 (0.31) | — | |
| SCHEMBL3399170 | 0.69 | TRPV1 (0.41) | — | |
| SCHEMBL9861848 | 0.69 | PTGS1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104643-A1 | PRESERVATIVE COMPOSITION | CURIOUS D.O.O. (HR) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021104643-A1 | PRESERVATIVE COMPOSITION | CURIOUS D.O.O. (HR) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021104643-A1 | PRESERVATIVE COMPOSITION | CURIOUS D.O.O. (HR) | 2021-06-03 | — | — | WO | disclosed |
| EP-2646037-B1 | use of polyanions to inhibit the cytotoxic activity of histones in the treatment of sepsis. | UNIV AUSTRALIAN NATIONAL (AU) | 2019-01-09 | — | — | EP | disclosed |
| CN-103402526-B | Histone suppresses | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2016-01-20 | — | — | CN | disclosed |
| US-9226939-B2 | Histone inhibition | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2016-01-05 | — | — | US | disclosed |
| US-20130338097-A1 | HISTONE INHIBITION | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2013-12-19 | — | — | US | disclosed |
| CN-103402526-A | Histone inhibition | UNIV AUSTRALIAN | 2013-11-20 | — | — | CN | disclosed |