Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206134 | 0.98 | PTGS1 (0.38) | PTGS1KCNH2TRPV1TRPA1CYP2D6 | |
| SCHEMBL6900018 | 0.98 | PTGS1 (0.38) | PTGS1KCNH2TRPV1TRPA1CYP2D6 | |
| SCHEMBL9861848 | 0.98 | PTGS1 (0.38) | PTGS1KCNH2TRPV1TRPA1CYP2D6 | |
| SCHEMBL2152238 | 0.93 | PTGS1 (0.40) | PTGS1KCNH2TRPV1TRPA1PTPN1 | |
| SCHEMBL5886044 | 0.84 | DPP4 (0.35) | PTGS1KCNH2 | |
| SCHEMBL2467052 | 0.76 | PTGS1 (0.40) | PTGS1KCNH2TRPA1LMNA | |
| SCHEMBL3399170 | 0.72 | TRPV1 (0.41) | TRPV1TRPA1CYP2D6SPHK1GMNN | |
| SCHEMBL11883270 | 0.72 | PTGS1 (0.37) | PTGS1KCNH2TRPA1 | |
| SCHEMBL23409649 | 0.71 | — | — | |
| SCHEMBL16100685 | 0.71 | TRPA1 (0.35) | PTGS1KCNH2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2939695-B1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS INC (CA) | 2018-08-29 | — | — | EP | disclosed |
| EP-2939695-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | Interface Biologics Inc. (CA) | 2015-11-04 | — | — | EP | disclosed |
| EP-1744787-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | Interface Biologics Inc. (CA) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005110485-A1 | POLYMERIC COUPLING AGENTS AND PHARMACEUTICALLY-ACTIVE POLYMERS MADE THEREFROM | INTERFACE BIOLOGICS INC. (CA) | 2005-11-24 | — | — | WO | disclosed |