Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | CYBB | P04839 | 2/20 | 0.45 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412188 | 0.94 | NCF1 (0.51) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL23412378 | 0.92 | MAPT (0.52) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL96224 | 0.92 | NCF1 (0.51) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL2163572 | 0.92 | KCNA3 (0.59) | NCF1MAPTHTR1BHTR1DSLC6A4 | |
| SCHEMBL2164367 | 0.92 | NCF1 (0.51) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL10950611 | 0.92 | NCF1 (0.51) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL10945765 | 0.92 | NCF1 (0.51) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL8058421 | 0.91 | NCF1 (0.50) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL9186984 | 0.90 | NCF1 (0.49) | NCF1MAPTKDM4EHTR1AHTR1B | |
| SCHEMBL96005 | 0.90 | NCF1 (0.49) | NCF1MAPTKDM4EHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021105497-A1 | SMALL-MOLECULE NADPH OXIDASE 2 INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2021-06-03 | — | — | WO | disclosed |