Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945765 | 1.00 | NCF1 (0.51) | NCF1MCHR1TLR8PDE5APDE4A | |
| SCHEMBL827493 | 0.94 | HTR1B (0.47) | NCF1MCHR1TLR8PDE5APDE4A | |
| SCHEMBL23412437 | 0.92 | NCF1 (0.58) | NCF1HTR1BHTR1DHTR1AMEN1 | |
| SCHEMBL7590766 | 0.89 | TLR8 (0.51) | NCF1TLR8HTR1ACNR1CNR2 | |
| SCHEMBL9969535 | 0.89 | HTR1B (0.48) | NCF1MCHR1TLR8HTR1BHTR1D | |
| SCHEMBL29872827 | 0.89 | HTR1B (0.48) | NCF1MCHR1TLR8HTR1BHTR1D | |
| SCHEMBL7561580 | 0.87 | TLR8 (0.50) | NCF1TLR8HTR1BCNR1CNR2 | |
| SCHEMBL23412188 | 0.87 | NCF1 (0.51) | NCF1HTR1BHTR1DHTR1AMEN1 | |
| SCHEMBL23412378 | 0.85 | MAPT (0.52) | NCF1HTR1BHTR1DHTR1AMEN1 | |
| SCHEMBL2163572 | 0.84 | KCNA3 (0.59) | NCF1HTR1BHTR1DMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554279-A | PLASMODICIDAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1985-11-19 | — | — | US | disclosed |