Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 6/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.55 |
| ▸ | IL23R | Q5VWK5 | 9/20 | 0.54 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23417933 | 0.93 | NPBWR1 (0.52) | MC4RNPBWR1IL23RKISS1R | |
| SCHEMBL26422011 | 0.92 | MC4R (0.55) | MC4RNPBWR1IL23RKISS1R | |
| SCHEMBL28058267 | 0.89 | MC4R (0.60) | MC4RIL23RKISS1R | |
| SCHEMBL28058268 | 0.89 | MC4R (0.60) | MC4RIL23RKISS1R | |
| SCHEMBL23417874 | 0.89 | MC4R (0.52) | MC4RNPBWR1IL23R | |
| SCHEMBL28235858 | 0.88 | ACE (0.57) | MC4R | |
| SCHEMBL17350015 | 0.88 | IL23R (0.56) | MC4RNPBWR1IL23R | |
| SCHEMBL20694561 | 0.88 | PRMT1 (0.54) | MC4RNPBWR1KISS1R | |
| SCHEMBL30518104 | 0.88 | IL23R (0.63) | MC4RNPBWR1IL23R | |
| SCHEMBL13599545 | 0.87 | MC4R (0.56) | MC4RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |