SCHEMBL26422011

SCHEMBL26422011

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)C(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 6/20 0.55
▸ IL23R Q5VWK5 10/20 0.51
▸ NPBWR1 P48145 1/20 0.51
▸ KISS1R Q969F8 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26421988 0.93 NPBWR1 (0.52) MC4RIL23RNPBWR1KISS1R
SCHEMBL24919242 0.92 NPBWR1 (0.49) MC4RNPBWR1KISS1R
SCHEMBL23417784 0.92 MC4R (0.58) MC4RIL23RNPBWR1KISS1R
SCHEMBL26421705 0.86 CTSL (0.52) MC4RIL23R
SCHEMBL26421690 0.86 CTSL (0.52) MC4RIL23R
SCHEMBL22803171 0.86 PRMT1 (0.54) MC4RIL23RNPBWR1KISS1R
SCHEMBL23417874 0.86 MC4R (0.52) MC4RIL23RNPBWR1
SCHEMBL28235858 0.85 ACE (0.57) MC4R
SCHEMBL23417933 0.85 NPBWR1 (0.52) MC4RIL23RNPBWR1KISS1R
SCHEMBL20694561 0.85 PRMT1 (0.54) MC4RNPBWR1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 MC4R 4124/4885IL23R 2886/4885NPBWR1 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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