Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1133673 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL31473002 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10389453 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10580785 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10579961 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10579987 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL1133981 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL10606386 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL1133699 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL30276919 | 1.00 | LMNA (0.76) | LMNADNM1HTTPLA2G1BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8597508-B2 | Sol-gel monolithic column with optical window and method of making | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-12-03 | — | — | US | disclosed |
| US-20120000850-A1 | SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-01-05 | — | — | US | disclosed |
| US-7947174-B2 | Sol-gel monolithic column with optical window and method of making | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-05-24 | — | — | US | disclosed |
| US-7850861-B1 | Microfluidic device, and related methods | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2010-12-14 | — | — | US | disclosed |
| US-20030213732-A1 | Sol-Gel monolithic column with optical window and method of making | SOUTH FLORIDA, UNIVERSITY OF | 2003-11-20 | — | — | US | disclosed |
| WO-2001058562-A1 | SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING | UNIVERSITY OF SOUTH FLORIDA (US) | 2001-08-16 | — | — | WO | disclosed |