SCHEMBL23419310

SCHEMBL23419310

NC(CNC(=O)/C=C/C1=C/C=C\C=C\C=C/1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GFPT1 Q06210 1/20 0.48
▸ CASR P41180 4/20 0.37
▸ MMP1 P03956 1/20 0.33
▸ MMP2 P08253 1/20 0.33
▸ MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23392471 1.00 GFPT1 (0.48) GFPT1CASRMMP1MMP2MMP9
SCHEMBL23453253 0.81 HPGD (0.33) GFPT1CASRMMP1MMP2MMP9
SCHEMBL23419681 0.79 SLC6A19 (0.33) GFPT1MMP1MMP2MMP9
SCHEMBL23419431 0.79 SMN1; SMN2 (0.34) GFPT1MMP1MMP2MMP9
SCHEMBL26050490 0.78 HPGD (0.32) MMP1MMP2MMP9
SCHEMBL27442074 0.77 HPGD (0.33) —
SCHEMBL6712571 0.74 KMT2A (0.59) GFPT1MMP1MMP2MMP9
SCHEMBL6712570 0.74 KMT2A (0.59) GFPT1MMP1MMP2MMP9
SCHEMBL23392466 0.72 CASR (0.40) CASR
SCHEMBL23419464 0.72 CASR (0.40) CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031178-B2 Cyclooctatetraene containing dyes and compositions ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-09 — — US disclosed
US-12031178-B2 Cyclooctatetraene containing dyes and compositions ILLUMINA CAMBRIDGE LIMITED (GB) 2024-07-09 — — US disclosed
US-20230265503-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20230265503-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20230265502-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
US-20230265502-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-08-24 — — US disclosed
WO-2021104845-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-06-03 — — WO disclosed
US-20210155983-A1 CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-05-27 — — US disclosed
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