SCHEMBL234252

SCHEMBL234252

CCCO[C@@H](C=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
AKR1B1 P15121 1/20 0.32
KDM4E B2RXH2 2/20 0.31
PDE4A P27815 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528201 0.95 LMNA (0.39) LMNAL3MBTL1TDP1AKR1B1KDM4E
SCHEMBL999357 0.89 ALDH1A1 (0.35) LMNAL3MBTL1TDP1USP2
SCHEMBL2559273 0.89 LMNA (0.39) LMNAL3MBTL1TDP1AKR1B1PDE4A
SCHEMBL28758113 0.86 USP2 (0.41) LMNAKDM4EUSP2
SCHEMBL7556267 0.86 USP2 (0.41) LMNAKDM4EUSP2
SCHEMBL15966786 0.85 LMNA (0.39) LMNAL3MBTL1TDP1AKR1B1KDM4E
SCHEMBL8332379 0.85 LMNA (0.39) LMNAL3MBTL1TDP1AKR1B1KDM4E
SCHEMBL183848 0.84 LMNA (0.34) LMNAL3MBTL1TDP1AKR1B1KDM4E
SCHEMBL9476977 0.83 LMNA (0.42) LMNAL3MBTL1TDP1AKR1B1KDM4E
SCHEMBL27832494 0.83 LMNA (0.42) LMNAL3MBTL1TDP1AKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 542 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9186399-B2 Immune stimulatory oligonucleotide analogs containing modified sugar moieties AdiutTide Pharmaceuticals GmbH (DE) 2015-11-17 US claimed
EP-2197488-B1 IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES ADIUTIDE PHARMACEUTICALS GMBH (DE) 2014-05-07 EP claimed
US-20110098456-A1 IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES ADIUTIDE PHARMACEUTICALS GMBH (DE) 2011-04-28 US claimed
JP-2011500014-A 2011-01-06 JP claimed
EP-2197488-A1 IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES Coley Pharmaceuticals GmbH (DE) 2010-06-23 EP claimed
WO-2009047610-A1 IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES COLEY PHARMACEUTICAL GMBH (DE) 2009-04-16 WO claimed
US-20080050745-A1 Sugar chain synthesizing agent having beta1,3-N-acetyglucosaminyltransferase activity KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-02-28 US claimed
US-20080044425-A1 POLYPEPTIDES HAVING PHOSPHOLIPASE A2 ACTIVITY KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-02-21 US claimed
US-20080015165-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-01-17 US claimed
US-7291491-B2 Having poly-N-acetyllactosamine sugar chains synthesis-related activity; use in antiinflammation, antiinfection, inhibition of cancer metastasis KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-11-06 US claimed
EP-1180525-B1 TRANSCRIPTIONAL ACTIVATION INHIBITORY PROTEIN KYOWA HAKKO KOGYO KK (JP) 2007-01-24 EP claimed
US-20040014089-A1 Polypeptides having phospholipase a2 activity KYOWA HAKKO KIRIN CO., LTD. (JP) 2004-01-22 US claimed
US-20030166208-A1 Novel polypeptides KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-09-04 US claimed
EP-1329511-A1 POLYPEPTIDE HAVING PHOSPHOLIPASE A2 ACTIIVTY KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-23 EP claimed
EP-1197556-A1 USEFUL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2002-04-17 EP claimed
EP-1162269-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-12-12 EP claimed
EP-1134230-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-09-19 EP claimed
EP-1108725-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-06-20 EP claimed
EP-1103604-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-05-30 EP claimed
EP-0937775-A2 Beta 1,3-N-acetylglucosaminyltransferase, DNA encoding it and its use KYOWA HAKKO KOGYO CO., LTD. (JP) 1999-08-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098456-A1 IMMUNE STIMULATORY OLIGONUCLEOTIDE ANALOGS CONTAINING MODIFIED SUGAR MOIETIES NT5C2, TLR3, TLR9 LMNA 4781/4885L3MBTL1 4180/4885TDP1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.