SCHEMBL234266

SCHEMBL234266

CCNC(NCC)[SiH2]NC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.35
EPHX1 P07099 3/20 0.33
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233727 0.98 SHBG (0.32) SHBGEPHX1
SCHEMBL231662 0.77 ALDH1A1 (0.36) SHBGEPHX1KDM4EALDH1A1HSD17B10
SCHEMBL235536 0.75 ALDH1A1 (0.35) EPHX1KDM4EALDH1A1HSD17B10
SCHEMBL233951 0.74 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL234792 0.72 ALDH1A1 (0.31) ALDH1A1HSD17B10
SCHEMBL16034979 0.72 ALDH1A1 (0.39) EPHX1KDM4EALDH1A1HSD17B10
SCHEMBL232357 0.71 SHBG (0.33) SHBG
SCHEMBL796282 0.71 ALDH1A1 (0.43) EPHX1KDM4EALDH1A1HSD17B10
SCHEMBL27966981 0.68 ALDH1A1 (0.36) SHBGEPHX1KDM4EALDH1A1HSD17B10
SCHEMBL236071 0.68 SHBG (0.30) SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed