Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NAT1 | P18440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666926 | 0.84 | DRD1 (0.60) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL29213631 | 0.84 | CNR2 (0.46) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL29733602 | 0.82 | DRD1 (0.58) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL29733609 | 0.82 | DRD1 (0.58) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL35966 | 0.80 | ALDH1A1 (0.59) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL27882659 | 0.79 | CYP2A6 (0.58) | CYP2A6HSD17B10MAOBALDH1A1ERN1 | |
| SCHEMBL8757864 | 0.79 | CYP2A6 (0.58) | CYP2A6DRD1HSD17B10MAOBALDH1A1 | |
| SCHEMBL4036224 | 0.79 | CYP2A6 (0.52) | CYP2A6ALDH1A1ERN1TNKS2SCN9A | |
| Hydrogen Sulfide SCHEMBL27896687 | 0.78 | ALDH1A1 (0.56) | CYP2A6DRD1DRD2DRD4DRD5 | |
| SCHEMBL26122642 | 0.78 | ALDH1A1 (0.57) | CYP2A6HSD17B10ALDH1A1ERN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075480-A4 | PURIFICATION OF CARBOXALDEHYDE | LILLY CO ELI (US) | 2002-01-23 | — | — | EP | claimed |
| EP-1075480-A1 | PURIFICATION OF CARBOXALDEHYDE | ELI LILLY AND COMPANY (US) | 2001-02-14 | — | — | EP | claimed |
| WO-1999057123-A1 | PURIFICATION OF CARBOXALDEHYDE | ELI LILLY AND COMPANY (US) | 1999-11-11 | — | — | WO | claimed |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| CN-107206050-A | High-purity oritavancin and production method thereof | 医药公司 | 2017-09-26 | — | — | CN | disclosed |
| US-20140121213-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2014-05-01 | — | — | US | disclosed |
| US-20140121213-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED (GB) | 2014-05-01 | — | — | US | disclosed |
| CN-101413143-B | Compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding | SCRIPPS RESEARCH INST | 2013-09-18 | — | — | CN | disclosed |
| CN-102105461-B | Insecticidal phenyl- or pyridyl-piperidine compounds | SYNGENTA PARTICIPATIONS AG | 2013-07-10 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-20130023541-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | GLAXO GROUP LIMITED | 2013-01-24 | — | — | US | disclosed |
| WO-2002057257-A1 | CYCLO`C!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREFOR | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |
| WO-2002057258-A1 | CYCLO`D!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREOF | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |
| EP-1225170-A2 | Cycloheptene compounds, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier S.A. (FR) | 2002-07-24 | — | — | EP | disclosed |
| WO-2002024649-A1 | SUBSTITUTED AMINO-AZA-CYCLOALKANES USEFUL AGAINST MALARIA | ACTELION PHARMACEUTICALS LTD (CH) | 2002-03-28 | — | — | WO | disclosed |
| EP-1075480-A4 | PURIFICATION OF CARBOXALDEHYDE | LILLY CO ELI (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1075480-A1 | PURIFICATION OF CARBOXALDEHYDE | ELI LILLY AND COMPANY (US) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999057123-A1 | PURIFICATION OF CARBOXALDEHYDE | ELI LILLY AND COMPANY (US) | 1999-11-11 | — | — | WO | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | CYP2A6 268/4885DRD1 1536/4885DRD2 1408/4885 |
| US-20130023541-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | KCNB1, KCNB2, SCNN1B | CYP2A6 2295/4885DRD1 2966/4885DRD2 2023/4885 |
| US-20140121213-A1 | VOLTAGE-GATED SODIUM CHANNEL BLOCKERS | KCNB1, SCNN1B, TRPV1 | CYP2A6 2174/4885DRD1 3127/4885DRD2 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.