Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.66 |
| ▸ | HTR2B | P41595 | 8/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343564 | 1.00 | HTR2C (0.66) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2344178 | 1.00 | HTR2C (0.66) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4317194 | 0.95 | HTR2C (0.69) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4317199 | 0.95 | HTR2C (0.69) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3809688 | 0.89 | CHRNB2 (0.63) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL187857 | 0.89 | HRH1 (0.66) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL1808272 | 0.87 | HRH1 (0.63) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL21071433 | 0.85 | HRH1 (0.61) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL232806 | 0.84 | SLC6A4 (0.63) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4317187 | 0.84 | HRH1 (0.59) | HTR2CHTR2BSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536697-B1 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | DAE WOONG PHARMA (KR) | 2016-10-19 | — | — | EP | disclosed |
| CN-102762542-B | Novel antifungal triazole derivatives | DAE WOONG PHARMA | 2015-07-22 | — | — | CN | disclosed |
| US-8940768-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-01-27 | — | — | US | disclosed |
| EP-2536697-A2 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | Daewoong Pharmaceutical Co., Ltd (KR) | 2012-12-26 | — | — | EP | disclosed |
| US-20120309771-A1 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2012-12-06 | — | — | US | disclosed |
| CN-102762542-A | Novel antifungal triazole derivatives | DAE WOONG PHARMA | 2012-10-31 | — | — | CN | disclosed |
| WO-2011099804-A2 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309771-A1 | NOVEL ANTIFUNGAL TRIAZOLE DERIVATIVES | ERG28, CYP51A1, DPM1 | HTR2C 4440/4885HTR2B 4593/4885SLC6A4 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.