Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23877336 | 0.91 | C5AR1 (0.47) | C5AR1FFAR1PPARDMAOBCYP2D6 | |
| SCHEMBL11247509 | 0.84 | LMNA (0.58) | MAOBSLC6A2 | |
| SCHEMBL31167023 | 0.84 | PTPN1 (0.49) | FFAR1PPARDMAOBCYP2D6HRH1 | |
| SCHEMBL13412635 | 0.84 | ALOX5 (0.63) | MAOBTOP1ALOX5SLC6A2 | |
| SCHEMBL5348078 | 0.83 | MAOB (0.60) | FFAR1PPARDMAOBCYP2D6HRH1 | |
| SCHEMBL8730031 | 0.82 | TDP1 (0.57) | MAOBTOP1ALOX5 | |
| SCHEMBL8730039 | 0.82 | TDP1 (0.57) | MAOBTOP1ALOX5 | |
| SCHEMBL21657603 | 0.82 | TDP1 (0.57) | MAOBTOP1ALOX5 | |
| SCHEMBL30628474 | 0.82 | TDP1 (0.57) | MAOBTOP1ALOX5 | |
| SCHEMBL29721135 | 0.82 | TDP1 (0.57) | MAOBTOP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828163-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | Protech Co., Ltd. (KR) | 2021-06-02 | — | — | EP | disclosed |