Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 7/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | GCGR | P47871 | 7/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23437869 | 0.85 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL23437873 | 0.80 | GCGR (0.50) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL23407682 | 0.80 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL29620839 | 0.80 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL14053997 | 0.80 | CCNB2 (0.50) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL23437868 | 0.79 | MAPK14 (0.49) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL7041734 | 0.78 | KDM4E (0.67) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL23437867 | 0.74 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL725362 | 0.73 | KDM4E (0.60) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL3956357 | 0.73 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345694-B2 | Antibacterial compounds | DISCUVA LTD. (GB) | 2022-05-31 | — | — | US | disclosed |
| US-20210163460-A1 | ANTIBACTERIAL COMPOUNDS | DISCUVA LTD. (GB) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345694-B2 | Antibacterial compounds | CFTR, MRPL21, NQO1 | MAPK13 3687/4885MAPK12 2492/4885MAPK11 2570/4885 |
| US-20210163460-A1 | ANTIBACTERIAL COMPOUNDS | CFTR, MRPL21, NQO1 | MAPK13 3687/4885MAPK12 2492/4885MAPK11 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.