Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 10/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.38 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | BLVRB | P30043 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23439886 | 0.86 | RXRA (0.38) | CYP26A1CYP26B1RXRAMEN1PGR | |
| SCHEMBL24562457 | 0.83 | PDK2 (0.36) | CYP26A1CYP26B1RXRAMAPK14MEN1 | |
| SCHEMBL29640027 | 0.83 | PDK2 (0.36) | CYP26A1CYP26B1RXRAMAPK14MEN1 | |
| SCHEMBL23439520 | 0.83 | RXRA (0.38) | CYP26A1CYP26B1RXRAMEN1PGR | |
| SCHEMBL23439324 | 0.82 | CYP26A1 (0.42) | CYP26A1CYP26B1RXRAMAPK14MEN1 | |
| SCHEMBL23439027 | 0.82 | CYP26A1 (0.46) | CYP26A1CYP26B1RXRAMAPK14MEN1 | |
| SCHEMBL24561711 | 0.81 | CYP26A1 (0.36) | CYP26A1CYP26B1RXRAMEN1PGR | |
| SCHEMBL23371572 | 0.79 | CYP26A1 (0.44) | CYP26A1CYP26B1RXRAMEN1PGR | |
| SCHEMBL23927549 | 0.78 | KIF11 (0.41) | CYP26A1CYP26B1RXRAMAPK14HDAC3 | |
| SCHEMBL23421097 | 0.77 | CYP26A1 (0.38) | CYP26A1CYP26B1RXRAMEN1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021107711-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | 주식회사 엘지화학 | 2021-06-03 | — | — | WO | disclosed |