Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.48 |
| ▸ | PLK1 | P53350 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23442648 | 0.93 | EGFR (0.46) | EGFRPLK1ALK | |
| SCHEMBL23420449 | 0.89 | EGFR (0.58) | EGFRPLK1ALK | |
| SCHEMBL23420447 | 0.89 | EGFR (0.58) | EGFRPLK1ALK | |
| SCHEMBL23441914 | 0.84 | EGFR (0.53) | EGFR | |
| SCHEMBL23441888 | 0.84 | EGFR (0.61) | EGFRPLK1 | |
| SCHEMBL23421625 | 0.82 | EGFR (0.55) | EGFRPLK1 | |
| SCHEMBL23421624 | 0.82 | EGFR (0.55) | EGFRPLK1 | |
| SCHEMBL23442890 | 0.81 | EGFR (0.53) | EGFRPLK1ALK | |
| SCHEMBL23420738 | 0.81 | EGFR (0.61) | EGFRPLK1ALK | |
| SCHEMBL22595153 | 0.79 | EGFR (0.47) | EGFRPLK1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104441-A1 | POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR | 江苏先声药业有限公司 | 2021-06-03 | — | — | WO | disclosed |