Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23441900 | 0.90 | EGFR (0.59) | EGFRBTK | |
| SCHEMBL23420406 | 0.90 | EGFR (0.68) | EGFRBTK | |
| SCHEMBL23442003 | 0.90 | EGFR (0.61) | EGFRBTK | |
| Hydrochloric Acid SCHEMBL29094608 | 0.90 | EGFR (0.50) | EGFRBTK | |
| SCHEMBL25001704 | 0.86 | EGFR (0.63) | EGFRPLK1 | |
| Trifluoroacetic Acid SCHEMBL29094594 | 0.85 | EGFR (0.47) | EGFRBTK | |
| SCHEMBL23442002 | 0.84 | EGFR (0.48) | EGFRPLK1 | |
| SCHEMBL23442595 | 0.83 | ALK (0.52) | EGFR | |
| SCHEMBL23441671 | 0.83 | EGFR (0.51) | EGFRBTK | |
| SCHEMBL25002651 | 0.83 | EGFR (0.58) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104441-A1 | POLYAROMATIC COMPOUND AS EGFR KINASE INHIBITOR | 江苏先声药业有限公司 | 2021-06-03 | — | — | WO | disclosed |