Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.60 |
| ▸ | THRB | P10828 | 12/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23663177 | 0.83 | THRA (0.61) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL10408308 | 0.82 | THRA (0.55) | THRATHRBL3MBTL1ATMKMT2A | |
| SCHEMBL11471529 | 0.80 | THRA (0.54) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL11465964 | 0.78 | THRA (0.58) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL23663471 | 0.78 | THRA (0.60) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL23442810 | 0.78 | THRB (0.52) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL2921588 | 0.76 | THRA (1.00) | THRATHRBCYP2C9UGT1A1ABCG2 | |
| SCHEMBL23168580 | 0.76 | THRA (0.60) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL23168797 | 0.76 | THRA (0.65) | THRATHRBL3MBTL1CYP2C9UGT1A1 | |
| SCHEMBL29066220 | 0.76 | THRA (0.55) | THRATHRBL3MBTL1CYP2C9UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104288-A1 | 1,2,4-TRIAZINE-3,5-DIONE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 昆药集团股份有限公司 | 2021-06-03 | — | — | WO | disclosed |