SCHEMBL2344344

SCHEMBL2344344

CCCCOC(=O)C1=CCC1C(=O)OCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
ESR1 P03372 7/20 0.44
LMNA P02545 3/20 0.44
MAPK1 P28482 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44
NR1H2 P55055 1/20 0.44
RNASEL Q05823 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 1/20 0.43
PDE4D Q08499 1/20 0.43
CHRM2 P08172 4/20 0.43
CHRM4 P08173 4/20 0.43
CHRM5 P08912 4/20 0.43
CHRM1 P11229 4/20 0.43
CHRM3 P20309 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2345193 0.90 ALDH1A1 (0.43) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL30483867 0.82 L3MBTL1 (0.42) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL30483866 0.79 TSHR (0.43) TSHRL3MBTL1ESR1LMNAMAPK1
SCHEMBL30483859 0.77 ALDH1A1 (0.44) TSHRESR1LMNAMAPK1CYP3A4
SCHEMBL30483856 0.77 ALDH1A1 (0.44) TSHRESR1LMNAMAPK1CYP3A4
SCHEMBL819729 0.76 L3MBTL1 (0.40) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL818110 0.75 L3MBTL1 (0.41) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL818752 0.75 TSHR (0.40) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL820015 0.74 L3MBTL1 (0.40) TSHRL3MBTL1TDP1ESR1LMNA
SCHEMBL30483874 0.73 ALDH1A1 (0.39) TSHRL3MBTL1TDP1ESR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617424-B1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME KONICA MINOLTA OPTO INC (JP) 2012-08-15 EP disclosed
US-20110204531-A1 Method of Manufacturing Wafer Lens KONICA MINOLTA OPTO, INC. (JP) 2011-08-25 US disclosed
EP-2202739-A1 Diffraction optical device and optical pickup device using the same Konica Minolta Opto, Inc. (JP) 2010-06-30 EP disclosed
US-20080310284-A1 DIFFRACTIVE OPTICAL ELEMENT AND OPTICAL PICKUP APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-12-18 US disclosed
EP-1617424-A1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME Konica Minolta Opto, Inc. (JP) 2006-01-18 EP disclosed
US-20050063282-A1 Diffractive optical element and optical pickup apparatus KONICA MINOLTA OPTO, INC. 2005-03-24 US disclosed