Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235567 | 0.91 | LTA4H (0.49) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL23475268 | 0.89 | LTA4H (0.45) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL30565197 | 0.88 | LTA4H (0.48) | LTA4HMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL23447187 | 0.87 | MEN1 (0.44) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL24235721 | 0.87 | LTA4H (0.47) | LTA4HMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL24235612 | 0.86 | LTA4H (0.50) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL22300888 | 0.86 | LTA4H (0.64) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL23447186 | 0.85 | MEN1 (0.44) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL24235585 | 0.85 | LTA4H (0.47) | LTA4HPOLBGAAMEN1KMT2A | |
| SCHEMBL24235759 | 0.84 | MEN1 (0.45) | LTA4HMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |