SCHEMBL30565197

SCHEMBL30565197

CC(C)(C)OC(=O)CC[C@H](NC(=O)[C@@H](N)CCC(=O)OC(C)(C)C)C(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.48
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPT P10636 2/20 0.44
XBP1 P17861 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SYK P43405 1/20 0.43
MME P08473 1/20 0.43
ANPEP P15144 1/20 0.43
PSMB5 P28074 1/20 0.42
CTSS P25774 1/20 0.41
PPARA Q07869 1/20 0.41
CTSK P43235 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24235721 0.92 LTA4H (0.47) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL22301197 0.88 ALDH1A1 (0.51) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL17344012 0.88 ALDH1A1 (0.51) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL24235567 0.88 LTA4H (0.49) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL23447176 0.88 LTA4H (0.49) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL30902868 0.87 CTSK (0.51) SYKPSMB5CTSSCTSK
SCHEMBL29336406 0.86 SYK (0.55) ALDH1A1MAPTSYKCTSSPPARA
SCHEMBL29336412 0.86 SYK (0.55) ALDH1A1MAPTSYKCTSSPPARA
SCHEMBL17347888 0.86 ALDH1A1 (0.52) LTA4HMEN1ALDH1A1HPGDKMT2A
SCHEMBL24235585 0.86 LTA4H (0.47) LTA4HMEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025083205-A1 DRUG COMBINATION COMPRISING ANTI-CD37 ANTIBODY MAYTANSINE CONJUGATE AND BCL2 INHIBITOR OR PI3K INHIBITOR DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-04-24 WO disclosed
EP-4507734-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES Debiopharm Research & Manufacturing S.A. (CH) 2025-02-19 EP disclosed
WO-2023198884-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-10-19 WO disclosed