Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23463370 | 0.96 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL23446366 | 0.93 | KMT2A (0.46) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL23445990 | 0.92 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL24235590 | 0.90 | KMT2A (0.49) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL22300310 | 0.88 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL23447603 | 0.88 | MEN1 (0.43) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL23475284 | 0.85 | MEN1 (0.53) | KMT2AMEN1ALDH1A1HPGDCTSB | |
| SCHEMBL23446341 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL13996825 | 0.82 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1HPGDACE | |
| SCHEMBL28222599 | 0.82 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1HPGDACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021103342-A1 | POLYETHYLENE GLYCOL CONJUGATED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |
| WO-2021104120-A1 | POLYETHYLENE GLYCOL CONJUGATE MEDICAMENT, PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |