Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235590 | 0.96 | KMT2A (0.49) | MEN1ALDH1A1HPGDKMT2ACTSK | |
| SCHEMBL22300310 | 0.94 | ALDH1A1 (0.49) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL23446366 | 0.90 | KMT2A (0.46) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL23463370 | 0.88 | ALDH1A1 (0.45) | MEN1ALDH1A1HPGDKMT2ACTSB | |
| SCHEMBL28222599 | 0.86 | ALDH1A1 (0.48) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL13996825 | 0.86 | ALDH1A1 (0.48) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL23447185 | 0.85 | KMT2A (0.45) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL23447603 | 0.85 | MEN1 (0.43) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL26047547 | 0.81 | ALDH1A1 (0.49) | MEN1ALDH1A1HPGDKMT2ACCKBR | |
| SCHEMBL27312654 | 0.81 | FOLH1 (0.49) | MEN1ALDH1A1HPGDKMT2ACCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021109351-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-10 | — | — | WO | disclosed |