Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23448451 | 0.83 | FFAR1 (0.38) | PDE10A | |
| SCHEMBL23447278 | 0.79 | GCGR (0.35) | PDE10A | |
| SCHEMBL25973351 | 0.77 | PDE10A (0.36) | PDE10A | |
| SCHEMBL23447092 | 0.76 | CRHR1 (0.41) | — | |
| SCHEMBL23448453 | 0.76 | CNR1 (0.35) | PDE10A | |
| SCHEMBL23447270 | 0.75 | PDE10A (0.38) | PDE10A | |
| SCHEMBL23447080 | 0.74 | TMEM97 (0.43) | — | |
| SCHEMBL10304594 | 0.73 | PDE10A (0.43) | PDE10A | |
| SCHEMBL25973482 | 0.72 | GCGR (0.41) | PDE10APDE2A | |
| SCHEMBL23447218 | 0.71 | HSD11B1 (0.40) | PDE10APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065564-B1 | [ (1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL) OXY ] ACETIC ACID DERIVATIVES AND SALTS THEREOF, USEFUL OR CULTIVATING AGENTS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS SAFENERS | BAYER AG (DE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2021105101-A1 | [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, CROP PROTECTION COMPOSITIONS COMPRISING THEM, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-03 | — | — | WO | disclosed |