Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275832 | 0.82 | MMP1 (0.43) | RENKLK5TSHRALDH1A1THRB | |
| SCHEMBL23447587 | 0.76 | KLK5 (0.52) | LCKKLK5MDM4MDM2 | |
| SCHEMBL23447565 | 0.75 | LCK (0.50) | LCKTSHRALDH1A1THRBCYP2C9 | |
| SCHEMBL29488615 | 0.75 | REN (0.33) | RENKLK5 | |
| SCHEMBL20556385 | 0.75 | REN (0.33) | RENKLK5 | |
| SCHEMBL15723421 | 0.75 | REN (0.33) | RENKLK5 | |
| SCHEMBL20556363 | 0.72 | ESR1 (0.36) | RENTSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL20556364 | 0.72 | ESR1 (0.36) | RENTSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL15723419 | 0.72 | ESR1 (0.36) | RENTSHRALDH1A1NPSR1MEN1 | |
| SCHEMBL30389215 | 0.72 | REN (0.32) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021106000-A1 | PROCESS FOR MAKING BIARYL-BRIDGED CYCLIC PEPTIDES | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2021-06-03 | — | — | WO | disclosed |