⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430025 | 0.87 | — | — | |
| SCHEMBL6377360 | 0.87 | MAPK1 (0.32) | — | |
| SCHEMBL402404 | 0.84 | HSD17B10 (0.33) | — | |
| SCHEMBL8624047 | 0.84 | HSD17B10 (0.33) | — | |
| SCHEMBL22767333 | 0.79 | — | — | |
| SCHEMBL633176 | 0.76 | MAPK1 (0.40) | — | |
| SCHEMBL1703854 | 0.73 | — | — | |
| SCHEMBL8841260 | 0.71 | TP53 (0.35) | — | |
| SCHEMBL8173778 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL14001975 | 0.69 | TP53 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1232565-C | Terminal group-adjustable superbranched polyamide and its preparation method | UNIV SHANGHAI JIAOTONG (CN) | 2005-12-21 | — | — | CN | claimed |
| CN-1405200-A | Terminal hydroxy superbranched polyester | UNIV SHANGHAI COMMUNICATION (CN) | 2003-03-26 | — | — | CN | claimed |
| CN-1405205-A | Terminal group-adjustable superbranched polyamide and its preparation method | UNIV SHANGHAI COMMUNICATION (CN) | 2003-03-26 | — | — | CN | claimed |
| CN-119775168-A | Synthesis method of chiral cis (cis) -2-amino-1-cyclopropylcarboxylic acid | 杭州澳赛诺生物科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20130310389-A1 | SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS | CEPHALON, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| US-8524713-B2 | Substituted spirocyclic piperidine derivatives as histamine-3 (H3) receptor ligands | CEPHALON, INC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2566864-A2 | PYRIDAZINONES AS GPR119 AGONISTS | Boehringer Ingelheim International GmbH (DE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138427-A2 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| EP-2257553-B1 | SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS | CEPHALON INC (US) | 2011-08-31 | — | — | EP | disclosed |
| EP-2257553-A1 | SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS | Cephalon, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100298332-A1 | Substituted Spirocyclic Piperidine Derivatives as Histamine-3 (H3) Receptor Ligands | CEPHALON, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2009097309-A1 | SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS | CEPHALON, INC. (US) | 2009-08-06 | — | — | WO | disclosed |
| CN-1232565-C | Terminal group-adjustable superbranched polyamide and its preparation method | UNIV SHANGHAI JIAOTONG (CN) | 2005-12-21 | — | — | CN | disclosed |
| CN-1405200-A | Terminal hydroxy superbranched polyester | UNIV SHANGHAI COMMUNICATION (CN) | 2003-03-26 | — | — | CN | disclosed |
| CN-1405205-A | Terminal group-adjustable superbranched polyamide and its preparation method | UNIV SHANGHAI COMMUNICATION (CN) | 2003-03-26 | — | — | CN | disclosed |
| US-4009278-A | Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |