Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.35 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.35 |
| ▸ | PPP5C | P53041 | 1/20 | 0.35 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999502 | 0.87 | TP53 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL11164592 | 0.87 | TP53 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL2344957 | 0.71 | — | — | |
| SCHEMBL11757532 | 0.71 | TP53 (0.41) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL2157390 | 0.71 | TP53 (0.31) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL8625710 | 0.70 | TP53 (0.35) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL4579264 | 0.70 | — | — | |
| SCHEMBL6377360 | 0.67 | MAPK1 (0.32) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL430025 | 0.67 | — | — | |
| SCHEMBL11258471 | 0.67 | LMNA (0.42) | TP53CYP3A4MAPK1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596435-A | Liquid crystal display device | KABUSHIKI KAISHA TOSHIBA (JP) | 1997-01-21 | — | — | US | disclosed |
| US-5477360-A | Liquid crystal display device | KABUSHIKI KAISHA TOSHIBA (JP) | 1995-12-19 | — | — | US | disclosed |
| US-4467100-A | Epoxy resin compositions cured with imide-amine at ambient temperatures to afford products having useful properties at high temperatures | LORD CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4366302-A | HEAT RESISTANCE CURING AGENTS | LORD CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |
| US-4340715-A | Epoxy resin compositions cured with imide-amines | LORD CORPORATION (US) | 1982-07-20 | — | — | US | disclosed |