Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413355 | 0.79 | CRBN (0.55) | CRBNDDB1IKZF3 | |
| SCHEMBL23449034 | 0.75 | KMT2A (0.42) | REV1 | |
| SCHEMBL23413581 | 0.69 | CRBN (0.66) | CRBNDDB1IKZF3 | |
| SCHEMBL23413509 | 0.68 | CRBN (0.48) | CRBNDDB1IKZF3 | |
| SCHEMBL23413142 | 0.68 | CRBN (0.53) | CRBNDDB1IKZF3 | |
| SCHEMBL23413144 | 0.68 | CRBN (0.53) | CRBNDDB1IKZF3 | |
| SCHEMBL23413560 | 0.66 | CRBN (0.58) | CRBNDDB1IKZF3 | |
| SCHEMBL20812432 | 0.66 | CRBN (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL23513440 | 0.64 | CRBN (0.57) | CRBNDDB1IKZF3 | |
| SCHEMBL31619863 | 0.64 | DDB1 (0.64) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105335-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2021-06-03 | — | — | WO | disclosed |