Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23413471 | 0.77 | DAO (0.47) | KMT2ACASP3SENP8SENP7SENP6 | |
| SCHEMBL23450055 | 0.75 | CRBN (0.39) | REV1 | |
| SCHEMBL23413435 | 0.74 | REV1 (0.57) | RAB9AALDH1A1MAPK1GFERLMNA | |
| SCHEMBL18154026 | 0.63 | MEN1 (0.86) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL1947748 | 0.62 | HSD17B10 (0.63) | KMT2ACASP3SENP7MEN1RAB9A | |
| SCHEMBL10344698 | 0.60 | KMT2A (0.59) | KMT2AMEN1RAB9AALDH1A1GFER | |
| SCHEMBL2733197 | 0.60 | RAB9A (0.45) | RAB9AALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL10520043 | 0.60 | KMT2A (0.62) | KMT2AMEN1RAB9AALDH1A1LMNA | |
| SCHEMBL12074798 | 0.60 | KMT2A (0.62) | KMT2ACASP3SENP8SENP7SENP6 | |
| SCHEMBL11465091 | 0.60 | REV1 (0.77) | KMT2ARAB9AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105335-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2021-06-03 | — | — | WO | disclosed |