Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222734 | 0.81 | KDM4E (0.59) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL24281981 | 0.80 | KDM4E (0.57) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL22009883 | 0.78 | KDM4E (0.50) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL2014323 | 0.77 | LNPEP (0.56) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL25351231 | 0.77 | HDAC1 (0.55) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL192100 | 0.77 | KDM4E (0.72) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL29375113 | 0.77 | KDM4E (0.72) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL24265280 | 0.76 | HDAC1 (0.53) | HDAC1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL23450340 | 0.76 | VCAM1 (0.53) | ALDH1A1HPGDKMT2ANPSR1LMNA | |
| Hydrochloric Acid SCHEMBL1223871 | 0.75 | KDM4E (0.70) | HDAC1KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163455-A1 | GLP-1 Receptor Agonists and Uses Thereof | PFIZER INC. (US) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163455-A1 | GLP-1 Receptor Agonists and Uses Thereof | GLP1R, GIPR, GCGR | HDAC1 435/4885KDM4E 1142/4885ALDH1A1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.