Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601692 | 0.80 | EPHX1 (0.47) | SMN1; SMN2 | |
| SCHEMBL23442063 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 | |
| SCHEMBL23420002 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 | |
| SCHEMBL12878807 | 0.76 | EPHX1 (0.39) | KMT2ASMN1; SMN2HTT | |
| SCHEMBL24063869 | 0.75 | CASP2 (0.38) | — | |
| SCHEMBL2608244 | 0.73 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 | |
| SCHEMBL23568035 | 0.73 | MEN1 (0.43) | KMT2ATSHREPHX2HTTMAPT | |
| SCHEMBL15855130 | 0.72 | KMT2A (0.61) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 | |
| SCHEMBL24500990 | 0.72 | KMT2A (0.61) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 | |
| SCHEMBL13033063 | 0.72 | KMT2A (0.61) | ALDH1A1LMNAKMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021108662-A1 | COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF | DTX PHARMA, INC. (US) | 2021-06-03 | — | — | WO | disclosed |