SCHEMBL2345124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2343921	1.00	MAP4K4 (0.66)	MAP4K4HDAC1GPR119SUV39H2EIF2AK4
	SCHEMBL2343918	1.00	MAP4K4 (0.66)	MAP4K4HDAC1GPR119SUV39H2EIF2AK4
	SCHEMBL31703517	0.86	MAP4K4 (0.50)	MAP4K4HDAC1EIF2AK4DPP4NR1H2
	SCHEMBL2338338	0.83	MAP4K4 (0.56)	MAP4K4HDAC1GPR119SUV39H2EIF2AK4
	SCHEMBL2338334	0.83	MAP4K4 (0.56)	MAP4K4HDAC1GPR119SUV39H2EIF2AK4
	SCHEMBL2342450	0.83	MAP4K4 (0.56)	MAP4K4HDAC1GPR119SUV39H2EIF2AK4
	SCHEMBL31327927	0.82	MAP4K4 (0.62)	MAP4K4HDAC1GPR119SUV39H2HDAC2
	SCHEMBL31104931	0.82	MAP4K4 (0.62)	MAP4K4HDAC1GPR119SUV39H2HDAC2
	SCHEMBL31105213	0.82	MAP4K4 (0.62)	MAP4K4HDAC1GPR119SUV39H2HDAC2
	SCHEMBL30426722	0.82	MAP4K4 (0.62)	MAP4K4HDAC1GPR119SUV39H2HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.