Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.37 |
| ▸ | CDK2 | P24941 | 7/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 5/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632008 | 0.90 | UCHL1 (0.44) | UCHL1CNR2CCNE1CDK2CDK5 | |
| SCHEMBL17644063 | 0.90 | UCHL1 (0.44) | UCHL1CNR2CCNE1CDK2CDK5 | |
| SCHEMBL21283661 | 0.75 | CDK2 (0.46) | CNR2CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL20883081 | 0.75 | SMN1; SMN2 (0.59) | UCHL1CNR2CCNE1CDK2CDK5 | |
| SCHEMBL20239934 | 0.74 | USP30 (0.38) | UCHL1CCNE1CDK2CDK5SMN1; SMN2 | |
| SCHEMBL22522971 | 0.73 | SMN1; SMN2 (0.45) | UCHL1CNR2CCNE1CDK2CDK5 | |
| SCHEMBL17632106 | 0.72 | UCHL1 (0.72) | UCHL1 | |
| SCHEMBL17632101 | 0.72 | UCHL1 (0.72) | UCHL1 | |
| SCHEMBL21845349 | 0.71 | CCNE1 (0.36) | UCHL1CNR2CCNE1CDK2CDK5 | |
| SCHEMBL20877325 | 0.70 | UCHL1 (0.45) | UCHL1CNR2CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3828179-A1 | CYANOPYRROLIDINES AS DUB MODULATORS | Mission Therapeutics Limited (GB) | 2021-06-02 | — | — | EP | disclosed |