Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453256 | 0.95 | TSHR (0.36) | TSHRHPGDNAAANPC1RAB9A | |
| SCHEMBL23453254 | 0.88 | HDAC4 (0.33) | TSHRHPGDLMNAMEN1KMT2A | |
| SCHEMBL26385379 | 0.84 | NAAA (0.36) | TSHRHPGDNAAANPC1RAB9A | |
| SCHEMBL23419305 | 0.84 | PAOX (0.44) | ALDH1A1SMN1; SMN2MAPK1PKMALOX5 | |
| SCHEMBL23392477 | 0.84 | PAOX (0.44) | ALDH1A1SMN1; SMN2MAPK1PKMALOX5 | |
| SCHEMBL23419522 | 0.83 | TP53BP1 (0.44) | TSHRNAAANPC1RAB9AL3MBTL1 | |
| SCHEMBL23419423 | 0.82 | CA2 (0.35) | TSHRHPGDNAAANPC1RAB9A | |
| SCHEMBL23392478 | 0.80 | KDM4E (0.39) | TSHRMEN1KMT2AKDM4E | |
| SCHEMBL23419457 | 0.80 | KDM4E (0.39) | TSHRMEN1KMT2AKDM4E | |
| SCHEMBL25997457 | 0.80 | TDP1 (0.54) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003087-A1 | FLUORESCENT DYES CONTAINING FUSED TETRACYCLIC BIS-BORON HETEROCYCLE AND USES IN SEQUENCING | ILLUMINA, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| US-20230313292-A1 | CHROMENOQUINOLINE DYES AND USES IN SEQUENCING | ILLUMINA, INC. | 2023-10-05 | — | — | US | disclosed |
| WO-2023186819-A1 | CHROMENOQUINOLINE DYES AND USES IN SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-10-05 | — | — | WO | disclosed |
| WO-2022129437-A1 | LONG STOKES SHIFT CHROMENOQUINOLINE DYES AND USES IN SEQUENCING APPLICATIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129930-A1 | ALKYLPYRIDINIUM COUMARIN DYES AND USES IN SEQUENCING APPLICATIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2021104845-A1 | CYCLOOCTATETRAENE CONTAINING DYES AND COMPOSITIONS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-03 | — | — | WO | disclosed |