Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | EPX | P11678 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334806 | 0.91 | ESRRA (0.40) | ESRRAHTR2ASLC6A4KCNH2KDM4E | |
| SCHEMBL5179755 | 0.79 | SCN9A (0.43) | HTR2ASLC6A4KCNH2SCN9A | |
| SCHEMBL17355907 | 0.79 | TEAD4 (0.46) | HTR2ASLC6A4KCNH2MPOTPO | |
| SCHEMBL17351273 | 0.79 | MAPT (0.54) | HTR2ASLC6A4KCNH2SCN9AMPO | |
| SCHEMBL2337575 | 0.78 | TDP1 (0.44) | ESRRAKDM4EPOLBNR1H4L3MBTL1 | |
| SCHEMBL17351217 | 0.75 | L3MBTL1 (0.51) | HTR2ASLC6A4KCNH2L3MBTL1F2 | |
| SCHEMBL3304400 | 0.74 | HTR2A (0.52) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL2338697 | 0.72 | TBXA2R (0.41) | ESRRAPOLBNR1H4L3MBTL1MEN1 | |
| SCHEMBL2336047 | 0.71 | ESRRA (0.34) | ESRRAHTR2ASLC6A4KCNH2SCN9A | |
| SCHEMBL2336045 | 0.71 | ESRRA (0.34) | ESRRAHTR2ASLC6A4KCNH2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183296-B2 | Pesticide phenyloxy substituted phenylamidine derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-22 | — | — | US | disclosed |
| EP-1931622-B1 | PHENYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-24 | — | — | EP | disclosed |
| US-20090042994-A1 | PESTICIDE PHENYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-02-12 | — | — | US | disclosed |
| EP-1931622-A1 | PESTICIDE PHENYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES | Bayer CropScience AG (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007031508-A1 | PESTICIDE PHENYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042994-A1 | PESTICIDE PHENYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES | DDT, PFAS, PIR | ESRRA 4304/4885HTR2A 3230/4885SLC6A4 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.