SCHEMBL2345374

SCHEMBL2345374

O=C1c2ccccc2CC1c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.55
CYP19A1 P11511 5/20 0.51
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
HTR2B P41595 1/20 0.47
METAP1 P53582 4/20 0.46
NOS3 P29474 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785363 1.00 ACHE (0.55) ACHECYP19A1LMNATP53CYP1A2
SCHEMBL13176510 0.85 KDM4E (0.53) ACHECYP19A1TP53CYP1A2CYP3A4
SCHEMBL2920960 0.85 CYP19A1 (0.56) ACHECYP19A1MAPTMETAP1SMN1; SMN2
SCHEMBL8001882 0.85 RAB9A (0.53) ACHECYP19A1LMNAMAPTMAPK1
SCHEMBL30424074 0.81 METAP1 (0.49) ACHECYP19A1MAPTMAPK1METAP1
SCHEMBL14939674 0.81 HTR2A (0.47) ACHECYP19A1LMNAMAPTHTR2B
SCHEMBL30423621 0.81 ACHE (0.49) ACHECYP19A1MAPTMETAP1
SCHEMBL14939220 0.81 CYP19A1 (0.59) ACHECYP19A1LMNATP53MAPT
SCHEMBL31751995 0.81 CYP19A1 (0.59) ACHECYP19A1MAPTMETAP1
SCHEMBL9148955 0.81 CYP19A1 (0.59) ACHECYP19A1LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790076-B1 Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use BASELL POLYOLEFINE GMBH (DE) 2001-12-05 EP claimed
EP-0790076-A2 Catalysts containing metallocenes with arylsubstituted indenyl derivatives as ligands, process and intermediates for the preparation of these metallocenes and their use HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-20 EP claimed
US-4578509-A Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis MERCK & CO., INC. (US) 1986-03-25 US claimed
EP-0121872-A1 Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis MERCK & CO. INC. (US) 1984-10-17 EP claimed
JP-1075443-A None JP disclosed
US-20250387546-A1 LUBRICIOUS COATED MEDICAL DEVICES BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-12-25 US disclosed
CN-118221849-B Application of metallocene catalyst composition as catalyst in preparation of poly alpha olefin wax 亚培烯科技(上海)有限公司 2024-12-13 CN disclosed
CN-118221849-A Application of metallocene catalyst composition as catalyst in preparation of poly alpha olefin wax 亚培烯科技(上海)有限公司 2024-06-21 CN disclosed
CN-114375291-B Novel compounds for skin lightening 联合利华知识产权控股有限公司 2024-03-08 CN disclosed
EP-3790604-A1 LUBRICIOUS COATING COMPOSITIONS Boston Scientific Scimed Inc. (US) 2021-03-17 EP disclosed
EP-3021882-B2 LUBRICIOUS COATING COMPOSITIONS BOSTON SCIENT SCIMED INC (US) 2021-01-27 EP disclosed
CN-110621345-A Pulmonary hypertension treatment 索尼维有限公司 2019-12-27 CN disclosed
US-5770753-A ADDITION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-06-23 US disclosed
EP-0228145-B1 POLYPHOTOINITIATORS LOCTITE CORPORATION (US) 1992-03-18 EP disclosed
US-5093498-A Trifluoromethylbenzyl containing quaternary salts MERCK & CO., INC. (US) 1992-03-03 US disclosed
JP-S6475443-A PRODUCTION OF INDANONE DERIVATIVE SEKISUI CHEMICAL CO LTD 1989-03-22 JP disclosed
EP-0228145-A1 Polyphotoinitiators LOCTITE CORPORATION (US) 1987-07-08 EP disclosed
US-4587276-A Polyphotoinitiators LOCTITE CORPORATION (US) 1986-05-06 US disclosed
US-4578509-A Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis MERCK & CO., INC. (US) 1986-03-25 US disclosed
EP-0121872-A1 Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis MERCK & CO. INC. (US) 1984-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387546-A1 LUBRICIOUS COATED MEDICAL DEVICES UFM1, PWWP2B, UFL1 ACHE 4653/4885CYP19A1 3291/4885LMNA 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.