Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL20456923 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL22443181 | 0.98 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL15323421 | 0.98 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL5324670 | 0.98 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL15323749 | 0.96 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL27204501 | 0.96 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL571078 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL15324017 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL28838082 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ACYP3A4 | |
| Citric Acid SCHEMBL29658277 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-110462054-A | Culture medium is perfused | BOEHRINGER INGELHEIM INT | 2019-11-15 | — | — | CN | claimed |
| CN-102291988-B | EDDS and calcium ion are as the application of killing mollusk active reinforcing agent | INNOSPEC LTD. (GB) | 2015-09-30 | — | — | CN | claimed |
| CN-102291988-A | Use of edds and calcium ions as enhancers of molluscicidal activity | — | 2011-12-21 | — | — | CN | claimed |
| EP-1527338-B1 | METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS SOLUTIONS | INSTRUMENTATION LAB CO (US) | 2011-08-31 | — | — | EP | claimed |
| US-7378006-B2 | Aqueous solutions for reducing the rate of oxygen loss, and methods thereof | INSTRUMENTATION LABORATORY COMPANY (US) | 2008-05-27 | — | — | US | claimed |
| JP-2005534031-A | — | — | 2005-11-10 | — | — | JP | claimed |
| EP-1527338-A1 | COMPOSITIONS AND METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS | Instrumentation Laboratory Company (US) | 2005-05-04 | — | — | EP | claimed |
| CN-1163126-C | Enhancement of metal molluscicides by ethylene diamine disuccinic acid | W����ŵ�� | 2004-08-25 | — | — | CN | claimed |
| US-20040137633-A1 | for increasing accuracy and effective life span of an electrochemical sensor system with oxygen-containing calibration solutions | INSTRUMENTATION LABORATORY COMPANY | 2004-07-15 | — | — | US | claimed |
| WO-2004011931-A1 | COMPOSITIONS AND METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS | INSTRUMENTATION LABORATORY COMPANY (US) | 2004-02-05 | — | — | WO | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| CN-1290125-A | Enhancement of metal molluscicides by ethylene diamine disuccinic acid | NEUDORFF W GMBH KG (DE) | 2001-04-04 | — | — | CN | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-119979622-A | Method for extracting p-coumaric acid from ginseng residue | 吉林农业大学 | 2025-05-13 | — | — | CN | disclosed |
| US-5705482-A | HUMAN GROWTH HORMONE AND LEUCINE-HISTIDINE-LEUCINE TRIPEPTIDE MIXTURE; STORAGE STABILITY; GLANDULAR DISORDERS | NOVO NORDISK A/S (DK) | 1998-01-06 | — | — | US | disclosed |
| US-5571518-A | PROLIFERATION OF SKIN | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1996-11-05 | — | — | US | disclosed |
| US-3980679-A | Process for the manufacture of glycidyl ethers of monohydric or polyhydric phenols, having improved properties | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |