Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.89 |
| ▸ | USP2 | O75604 | 4/20 | 0.89 |
| ▸ | HAT1 | O14929 | 4/20 | 0.89 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.89 |
| ▸ | HTT | P42858 | 4/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.89 |
| ▸ | RECQL | P46063 | 3/20 | 0.89 |
| ▸ | CASP7 | P55210 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | CASP1 | P29466 | 2/20 | 0.89 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.89 |
| ▸ | TST | Q16762 | 2/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 1/20 | 0.89 |
| ▸ | HBB | P68871 | 1/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Riboflavin SCHEMBL27764352 | 0.96 | MEN1 (0.89) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL7135127 | 0.94 | MEN1 (0.92) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL2798981 | 0.94 | MEN1 (0.92) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL2127865 | 0.94 | MEN1 (0.92) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL2799507 | 0.94 | MEN1 (0.92) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL9609755 | 0.94 | MEN1 (1.00) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL7706 | 0.94 | MEN1 (1.00) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL2420598 | 0.94 | MEN1 (1.00) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL12979917 | 0.94 | MEN1 (1.00) | MEN1KMT2AUSP2HAT1RBBP7 | |
| Riboflavin SCHEMBL7707 | 0.94 | MEN1 (1.00) | MEN1KMT2AUSP2HAT1RBBP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230070210-A1 | Simulation Model Sample for Evaluation of Heat Treatment, and Method for Evaluating Heat Treatment Using Simulation Model Sample | HISAKA WORKS, LTD. (JP) | 2023-03-09 | — | — | US | disclosed |
| US-20230065570-A1 | Simulation Model Sample for Evaluation of Heat Treatment, and Method for Evaluating Heat Treatment Using Simulation Model Sample | HISAKA WORKS, LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| US-20230067351-A1 | Simulation Model Sample for Evaluation of Heat Treatment, and Method for Evaluating Heat Treatment Using Simulation Model Sample | HISAKA WORKS, LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| US-20210096091-A1 | Simulation Model Sample for Evaluation of Heat Treatment, and Method for Evaluating Heat Treatment Using Simulation Model Sample | HISAKA WORKS, LTD. (JP) | 2021-04-01 | — | — | US | disclosed |
| JP-2014196254-A | BOFUTSUSHOSAN-CONTAINING PREPARATION | 小林製薬株式会社 | 2014-10-16 | — | — | JP | disclosed |
| US-20110251417-A1 | Partially Hydrocarbon Group-Blocked (Poly)Glycerol-Modified Polysiloxane, Method For Producing The Same, And Cosmetic Composition Containing The Same | DOW TORAY CO., LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2361273-A1 | PARTIALLY HYDROCARBON GROUP-BLOCKED (POLY)GLYCEROL-MODIFIED POLYSILOXANE, METHOD FOR PRODUCING THE SAME, AND COSMETIC COMPOSITION CONTAINING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2011-08-31 | — | — | EP | disclosed |
| WO-2010074296-A1 | PARTIALLY HYDROCARBON GROUP-BLOCKED (POLY)GLYCEROL-MODIFIED POLYSILOXANE, METHOD FOR PRODUCING THE SAME, AND COSMETIC COMPOSITION CONTAINING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2010-07-01 | — | — | WO | disclosed |
| CN-1325036-C | Powder composition powder dispersion in oil and cosmetic composition containing said powder composition and powder dispersion in oil | KOSE CORP (JP) | 2007-07-11 | — | — | CN | disclosed |
| JP-2004091473-A | THERAPEUTIC AGENT FOR IMPROVING CHROMATOSIS | TAKADA TADAYASU | 2004-03-25 | — | — | JP | disclosed |
| EP-1029897-A1 | Organosilicon resin composition, method of making, and cosmetic composition containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-23 | — | — | EP | disclosed |
| EP-1008353-A1 | SACCHARIDE-CONTAINING COMPOSITIONS | FUJI CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-06-14 | — | — | EP | disclosed |
| JP-2000044470-A | HYPERLIPEMIA MEDICINE | NOF CORP | 2000-02-15 | — | — | JP | disclosed |
| EP-0972508-A1 | EXTRACELLULAR MATRIX PRODUCTION PROMOTER | SHISEIDO COMPANY LIMITED (JP) | 2000-01-19 | — | — | EP | disclosed |
| CN-1230398-A | Powder composition powder dispersion in oil and cosmetic composition containing said powder composition and powder dispersion in oil | KOSE CORP (JP) | 1999-10-06 | — | — | CN | disclosed |
| EP-0561195-B1 | An invigorating herbal gel for supple skin | SHISEIDO CO LTD (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5407677-A | Containing fennel extract, inositol, dextran sulfate | SHISEIDO CO., LTD. (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0561195-A1 | An invigorating herbal gel for supple skin | SHISEIDO COMPANY LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-4670185-A | ANIONIC, CATIONIC, NONIONIC SURFACTANTS | LION CORPORATION (JP) | 1987-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251417-A1 | Partially Hydrocarbon Group-Blocked (Poly)Glycerol-Modified Polysiloxane, Method For Producing The Same, And Cosmetic Composition Containing The Same | PFAS, NOTUM, FGB | MEN1 4360/4885KMT2A 519/4885USP2 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.