⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL2285565 | 1.00 | TTR (0.67) | — | |
| Dioxane SCHEMBL10791372 | 1.00 | TTR (0.67) | — | |
| Dioxane SCHEMBL11079749 | 0.95 | — | — | |
| Dioxane SCHEMBL11079311 | 0.95 | — | — | |
| Dioxane SCHEMBL11074566 | 0.95 | — | — | |
| Dioxane SCHEMBL11073120 | 0.95 | — | — | |
| Dioxane SCHEMBL3355965 | 0.95 | — | — | |
| Oxirane SCHEMBL844515 | 0.94 | — | — | |
| Dioxane SCHEMBL28216951 | 0.87 | ALDH1A1 (0.67) | — | |
| Dioxane SCHEMBL7807843 | 0.83 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 546 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116063159-B | Method for producing hydroquinone by phenol hydroxylation | 湖南长炼新材料科技股份公司 | 2024-07-16 | — | — | CN | claimed |
| CN-117362572-A | Novel phenolized modified lignin-based flame-retardant rigid polyurethane foam material and preparation method thereof | 青岛双星轮胎工业有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-107365295-B | Improved method of pomalidomide synthesis process | 常州制药厂有限公司 | 2020-07-07 | — | — | CN | claimed |
| WO-2018134842-A1 | PROCESS FOR THE PREPARATION OF CARBAMIC ACID, N,N'-[[1,1'-BIPHENYL] -4,4'-DIYLBIS]- 1 H-IMIDAZOLE-5,2 DIYI-(2S)-2,1-PYRROLIDINEDIYL[(1 S)-1-(1-METHYLETHYL)-2-OXO-2,1-ETHANEDIYL]]] BIS-,C,C'-DIMETHYL ESTER AND ITS SALTS AND POLYMORPHS | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2018-07-26 | — | — | WO | claimed |
| CN-105418616-A | JAK kinase inhibitor containing 4-aminopyrazole structure, preparation method and application thereof | UNIV SHANDONG | 2016-03-23 | — | — | CN | claimed |
| CN-103665356-B | A kind of continuous processing prepares the method for polyester resin for powder coating | ZHANGJIAGANG BAOTIAN NEW MATERIAL TECHNOLOGY CO.,LTD. (CN) | 2015-08-26 | — | — | CN | claimed |
| CN-103193765-B | 1,8-naphthalene imide derivative and preparation method and application thereof | UNIV SOOCHOW | 2014-07-02 | — | — | CN | claimed |
| CN-103665356-A | Preparation method for thermoset saturate polyester resin used in powder coating according to continuous method | ZHANGJIAGANG POLYLAND NEW MATERIALS TECHNOLOGY CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-103193765-A | 1,8-naphthalene imide derivative and preparation method and application thereof | UNIV SOOCHOW | 2013-07-10 | — | — | CN | claimed |
| CN-101712682-A | Method for synthesizing tasosartan | JIANGSU DEFENG PHARMACEUTICAL | 2010-05-26 | — | — | CN | claimed |
| CN-101648945-A | Synthesis of important irbesartan intermediate | JIANGSU DEFENG PHARMACEUTICAL | 2010-02-17 | — | — | CN | claimed |
| CN-101475564-A | Novel preparation of losartan potassium | JIANGSU DEFENG CHEMICAL INDUST (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101475540-A | Preparation of Valsartan | JIANGSU DEFENG CHEMICAL INDUST (CN) | 2009-07-08 | — | — | CN | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| US-5854408-A | Process for acylating the 1-position of saccharides | ENSUIKO SUGAR REFINING CO., LTD. (JP) | 1998-12-29 | — | — | US | claimed |
| US-4950750-A | Glycolipid containing N-glycolylneuraminic acid and method of producing the same | MECT CORPORATION (JP) | 1990-08-21 | — | — | US | claimed |
| CN-85103908-A | Preparation 4 '-novel method of the red rhzomorph of Biao Duokesuo | — | 1986-11-05 | — | — | CN | claimed |
| US-4587203-A | USING A DEVELOPMENT SOLVENT AND RINSING NONSOLVENT; SILANE COUPLING INTERLAYER; DIMENSIONAL STABILITY AND SHARPNESS OF IMAGE | HUGHES AIRCRAFT COMPANY (US) | 1986-05-06 | — | — | US | claimed |
| US-4535054-A | IRRADIATION TO GIVE NEGATIVE PATTERN IMAGE, DEVELOPMENT BY DISSOLUING UNEXPOSED POLYMER WITH SOLVENT AND RINSING | HUGHES AIRCRAFT COMPANY (US) | 1985-08-13 | — | — | US | claimed |
| JP-10195555-A | — | — | None | — | — | JP | disclosed |
| EP-4081521-B1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LTD (IN) | 2025-12-10 | — | — | EP | disclosed |
| WO-2025061177-A1 | SMALL-MOLECULE DRUG FOR TREATING CGRP-RELATED DISORDER | 成都康弘药业集团股份有限公司 | 2025-03-27 | — | — | WO | disclosed |
| CN-119661518-A | Small molecule medicine for treating CGRP related disorder | 成都康弘药业集团股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20240366608-A1 | PHARMACEUTICAL COMBINATIONS OF SOS1 INHIBITORS FOR TREATING AND/OR PREVENTING CANCER | LUPIN LIMITED (IN) | 2024-11-07 | — | — | US | disclosed |
| US-20240234798-A1 | METHOD FOR PRODUCING SOLID ELECTROLYTE PARTICLES AND METHOD FOR PRODUCING ALL-SOLID-STATE BATTERY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240209129-A1 | OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF | Johnson & Johnson Surgical Vision, Inc. | 2024-06-27 | — | — | US | disclosed |
| US-20240194936-A1 | METHOD FOR PRODUCING SOLID ELECTROLYTE POWDER, AND METHOD FOR PRODUCING ALL SOLID STATE BATTERY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-06-13 | — | — | US | disclosed |
| WO-2024116106-A1 | OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF | Johnson & Johnson Surgical Vision, Inc. (US) | 2024-06-06 | — | — | WO | disclosed |
| CN-115605476-B | Substituted tricyclic compounds | 鲁宾有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240158418-A1 | EGFR Degraders to Treat Cancer Metastasis to the Brain or CNS | C4 THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| CN-113214066-B | Gossypol crystal II substance, preparation method, composition and application thereof | 中国医学科学院药物研究所 | 2024-05-14 | — | — | CN | disclosed |
| EP-4347044-A2 | EGFR DEGRADERS TO TREAT CANCER METASTASIS TO THE BRAIN OR CNS | C4 Therapeutics, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-4335439-A2 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-03-13 | — | — | EP | disclosed |
| US-20240076300-A1 | ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR | C4 THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | US | disclosed |
| EP-4321484-A1 | METHOD FOR PRODUCING SOLID ELECTROLYTE POWDER, AND METHOD FOR PRODUCING ALL SOLID STATE BATTERY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-02-14 | — | — | EP | disclosed |
| EP-4321485-A1 | METHOD FOR PRODUCING SOLID ELECTROLYTE PARTICLES AND METHOD FOR PRODUCING ALL-SOLID-STATE BATTERY | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-02-14 | — | — | EP | disclosed |
| CN-117377660-A | Process for the preparation of benzoxazepine oxazolidinone compounds | 基因泰克公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117362572-A | Novel phenolized modified lignin-based flame-retardant rigid polyurethane foam material and preparation method thereof | 青岛双星轮胎工业有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117362572-A | Novel phenolized modified lignin-based flame-retardant rigid polyurethane foam material and preparation method thereof | 青岛双星轮胎工业有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20230416256-A1 | SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE | JANSSEN PHARAMCEUTICA NV (BE) | 2023-12-28 | — | — | US | disclosed |
| EP-4281078-A1 | PHARMACEUTICAL COMBINATIONS OF SOS1 INHIBITORS FOR TREATING AND/OR PREVENTING CANCER | Lupin Limited (IN) | 2023-11-29 | — | — | EP | disclosed |
| CN-117063319-A | Method for producing solid electrolyte particles and method for producing all-solid battery | 三菱瓦斯化学株式会社 | 2023-11-14 | — | — | CN | disclosed |
| CN-117063320-A | Method for producing solid electrolyte powder and method for producing all-solid battery | 三菱瓦斯化学株式会社 | 2023-11-14 | — | — | CN | disclosed |
| US-11814378-B2 | Compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates | AC IMMUNE SA (CH) | 2023-11-14 | — | — | US | disclosed |
| EP-3810602-B1 | COMPOUNDS | CTXT PTY LTD (AU) | 2023-11-01 | — | — | EP | disclosed |
| US-11673902-B2 | Isoindolinone and indazole compounds for the degradation of EGFR | C4 THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230119316-A1 | Substituted Tricyclic Compounds | LUPIN LIMITED (IN) | 2023-04-20 | — | — | US | disclosed |
| US-20230122651-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2023-04-20 | — | — | US | disclosed |
| US-20230110648-A1 | ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR | C4 THERAPEUTICS, INC. (US) | 2023-04-13 | — | — | US | disclosed |
| US-20230031954-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | TETRAPHASE PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
| US-20230019060-A1 | HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | US | disclosed |
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |
| EP-4081521-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-11-02 | — | — | EP | disclosed |
| WO-2022215519-A1 | METHOD FOR PRODUCING SOLID ELECTROLYTE POWDER, AND METHOD FOR PRODUCING ALL SOLID STATE BATTERY | 三菱瓦斯化学株式会社 | 2022-10-13 | — | — | WO | disclosed |
| WO-2022157629-A1 | PHARMACEUTICAL COMBINATIONS OF SOS1 INHIBITORS FOR TREATING AND/OR PREVENTING CANCER | LUPIN LIMITED (IN) | 2022-07-28 | — | — | WO | disclosed |
| EP-4029854-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | Fibrogen, Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| CN-108329312-B | Tetracycline compounds | 四相制药公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-3470397-B1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN INC (US) | 2021-12-29 | — | — | EP | disclosed |
| US-11192866-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-12-07 | — | — | US | disclosed |
| CN-109415387-B | Arginase inhibitors and therapeutic uses thereof | 昂科艾伦迪治疗法公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-113214066-A | Gossypol crystal II substance, preparation method, composition and application thereof | 中国医学科学院药物研究所 | 2021-08-06 | — | — | CN | disclosed |
| WO-2021130731-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-01 | — | — | WO | disclosed |
| WO-2021127561-A1 | ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR | C4 THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| CN-106279023-B | 3,4, 5-trisubstituted pyrazole compound, preparation method, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2021-06-22 | — | — | CN | disclosed |
| US-20210161825-A1 | CHLOROQUINE-BASED MATERIALS FOR THE TREATMENT OF DISEASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-03 | — | — | US | disclosed |
| US-20210122709-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2021-04-29 | — | — | US | disclosed |
| US-10981896-B2 | Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-20 | — | — | US | disclosed |
| US-10912755-B2 | Arginase inhibitors and their therapeutic applications | Oncoarendi Therapeutics S.A. (PL) | 2021-02-09 | — | — | US | disclosed |
| US-10913712-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2021-02-09 | — | — | US | disclosed |
| US-10851058-B2 | Histone deacetylase inhibitors | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-20200369665-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-11-26 | — | — | US | disclosed |
| EP-3159349-B1 | LOBAPLATIN CRYSTAL, PREPARATION METHOD AND PHARMACEUTICAL APPLICATION | GUIZHOU YIBAI PHARMACEUTICAL CO LTD (CN) | 2020-08-05 | — | — | EP | disclosed |
| CN-107474026-B | Preparation method of 2, 5-diaminomethyl tetrahydrofuran | 中国科学院大连化学物理研究所 | 2020-08-04 | — | — | CN | disclosed |
| EP-3138831-B1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2020-07-08 | — | — | EP | disclosed |
| CN-107365295-B | Improved method of pomalidomide synthesis process | 常州制药厂有限公司 | 2020-07-07 | — | — | CN | disclosed |
| EP-2016044-B1 | PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | HARVARD COLLEGE (US) | 2020-06-10 | — | — | EP | disclosed |
| US-10669244-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200148679-A1 | Novel compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates | AC IMMUNE SA (CH) | 2020-05-14 | — | — | US | disclosed |
| US-10633383-B2 | Compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates | AC IMMUNE SA (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20200115344-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN INC (US) | 2020-04-16 | — | — | US | disclosed |
| US-20200087314-A1 | HISTONE DEACETYLASE INHIBITORS | BIOMARIN PHARMACEUTICAL INC. | 2020-03-19 | — | — | US | disclosed |
| US-20200055813-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2020-02-20 | — | — | US | disclosed |
| US-20200048193-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2020-02-13 | — | — | US | disclosed |
| US-20200039945-A1 | Compounds | CTXT PTY LIMITED (AU) | 2020-02-06 | — | — | US | disclosed |
| CN-107108782-B | Terminal-modified soluble polyfunctional vinyl aromatic co-polymer and its application | 日铁化学材料株式会社 | 2019-12-03 | — | — | CN | disclosed |
| US-20190345116-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190276408-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2019-09-12 | — | — | US | disclosed |
| US-10391077-B2 | Arginase inhibitors and their therapeutic applications | Oncoarendi Therapeutics S.A. (PL) | 2019-08-27 | — | — | US | disclosed |
| US-20190211012-A1 | Novel compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates | AC IMMUNE SA (CH) | 2019-07-11 | — | — | US | disclosed |
| EP-3506908-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | Tetraphase Pharmaceuticals, Inc. (US) | 2019-07-10 | — | — | EP | disclosed |
| US-10315992-B2 | Tetracyline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-10272078-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| CN-109689641-A | A kind of substituted 2- hydrogen-pyrazole derivatives crystal form, salt form and preparation method thereof | 正大天晴药业集团股份有限公司 | 2019-04-26 | — | — | CN | disclosed |
| EP-3470397-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | Fibrogen, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-3461809-A1 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| CN-109476641-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109415387-A | Arginase inhibitor and its treatment use | 昂科艾伦迪治疗法公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20190022080-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2019-01-24 | — | — | US | disclosed |
| US-20190000832-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | Selder Pharma Inc. (US) | 2019-01-03 | — | — | US | disclosed |
| US-20190002398-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2019-01-03 | — | — | US | disclosed |
| EP-2890673-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2018-11-14 | — | — | EP | disclosed |
| US-10118897-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180265613-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | GENZYME CORPORATION | 2018-09-20 | — | — | US | disclosed |
| WO-2018160967-A1 | INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-09-07 | — | — | WO | disclosed |
| CN-108473472-A | 2-aminoquinazoline derivatives as P70S6 kinase inhibitors | 圣提内尔肿瘤学有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-2872488-B1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN INC (US) | 2018-08-22 | — | — | EP | disclosed |
| WO-2018134842-A1 | PROCESS FOR THE PREPARATION OF CARBAMIC ACID, N,N'-[[1,1'-BIPHENYL] -4,4'-DIYLBIS]- 1 H-IMIDAZOLE-5,2 DIYI-(2S)-2,1-PYRROLIDINEDIYL[(1 S)-1-(1-METHYLETHYL)-2-OXO-2,1-ETHANEDIYL]]] BIS-,C,C'-DIMETHYL ESTER AND ITS SALTS AND POLYMORPHS | MSN LABORATORIES PRIVATE LIMITED, R & D CENTER (IN) | 2018-07-26 | — | — | WO | disclosed |
| US-10016410-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | SELDAR PHARMA INC. (US) | 2018-07-10 | — | — | US | disclosed |
| EP-2940020-B1 | LUCIFERIN LUMINESCENT SUBSTRATE OF MARINE OSTRACOD CRUSTACEAN AND METHOD FOR PRODUCTION THEREOF | AIST (JP) | 2018-04-25 | — | — | EP | disclosed |
| CN-103874700-B | Pyrazolo [3,4-c ] pyridine compounds and methods of use | 霍夫曼-拉罗奇有限公司 | 2018-03-30 | — | — | CN | disclosed |
| US-9918977-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| WO-2018045084-A1 | TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| US-9889112-B2 | Lobaplatin crystal, preparation method and pharmaceutical application | GUIZHOU YIBAI PHARMACEUTICAL COMPANY LIMITED (CN) | 2018-02-13 | — | — | US | disclosed |
| US-9884830-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-06 | — | — | US | disclosed |
| EP-3275861-A1 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| CN-107474026-A | A kind of preparation method of 2,5 diaminomethyl tetrahydrofuran | 中国科学院大连化学物理研究所 | 2017-12-15 | — | — | CN | disclosed |
| CN-107406805-A | Cold water laundry detergent | 斯泰潘公司 | 2017-11-28 | — | — | CN | disclosed |
| US-20170334841-A1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20170319536-A1 | Arginase Inhibitors and Their Therapeutic Applications | Oncoarendi Therapeutics S.A. (PL) | 2017-11-09 | — | — | US | disclosed |
| US-20170305852-A1 | Tetracyline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2017-10-26 | — | — | US | disclosed |
| EP-3000805-B1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-10-18 | — | — | EP | disclosed |
| EP-2470500-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-10-04 | — | — | EP | disclosed |
| US-20170275244-A1 | C7-Fluoro Substituted Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-09-28 | — | — | US | disclosed |
| CN-107108782-A | Terminal-modified soluble polyfunctional vinyl aromatic co-polymer, curable resin composition and use its light guide wave duct | 新日铁住金化学株式会社 | 2017-08-29 | — | — | CN | disclosed |
| US-20170189390-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170190667-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2017-07-06 | — | — | US | disclosed |
| US-20170189367-A1 | Lobaplatin Crystal, Preparation Method And Pharmaceutical Application | GUIZHOU YIBAI PHARMACEUTICAL COMPANY LIMITED (CN) | 2017-07-06 | — | — | US | disclosed |
| CN-106631975-A | Platinum complexes of S-methyldithiocarbazate derivatives of indolin-2-one and preparation method and application of platinum complexes | 首都师范大学 | 2017-05-10 | — | — | CN | disclosed |
| EP-3159349-A1 | LOBAPLATIN CRYSTAL, PREPARATION METHOD AND PHARMACEUTICAL APPLICATION | Guizhou Yibai Pharmaceutical Co., Ltd. (CN) | 2017-04-26 | — | — | EP | disclosed |
| US-9624166-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| US-9617218-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| EP-3138831-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | President and Fellows of Harvard College (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9573895-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| CN-106279023-A | 3,4,5-tri-substituted pyrazolecarboxylic compounds, preparation method, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2017-01-04 | — | — | CN | disclosed |
| US-9526719-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | SELDAR PHARMA INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20160340325-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-24 | — | — | US | disclosed |
| US-20160331741-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2016-11-17 | — | — | US | disclosed |
| CN-103596917-B | The manufacture method of cyclopentanone compound and midbody compound | 株式会社吴羽 | 2016-08-17 | — | — | CN | disclosed |
| CN-103224474-B | The synthesis of tetracycline and the like | 哈佛大学校长及研究员协会 | 2016-08-03 | — | — | CN | disclosed |
| EP-1753713-B1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2016-07-27 | — | — | EP | disclosed |
| US-9371288-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-9365493-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160107988-A1 | Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2016-04-21 | — | — | US | disclosed |
| EP-3000805-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2016-03-30 | — | — | EP | disclosed |
| CN-105418616-A | JAK kinase inhibitor containing 4-aminopyrazole structure, preparation method and application thereof | UNIV SHANDONG | 2016-03-23 | — | — | CN | disclosed |
| US-9259000-B2 | Auxin biosynthesis inhibitor | RIKEN (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20160024233-A1 | SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS | GENZYME CORPORATION | 2016-01-28 | — | — | US | disclosed |
| CN-105218516-A | Therapeutic compounds and related methods of use | OTSUKA PHARMA CO LTD | 2016-01-06 | — | — | CN | disclosed |
| US-20150359787-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC. (US) | 2015-12-17 | — | — | US | disclosed |
| US-20150322015-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2015-11-12 | — | — | US | disclosed |
| EP-2940020-A1 | LUCIFERIN LUMINESCENT SUBSTRATE OF MARINE OSTRACOD CRUSTACEAN AND METHOD FOR PRODUCTION THEREOF | National Institute of Advanced Industrial Science and Technology (JP) | 2015-11-04 | — | — | EP | disclosed |
| CN-103214409-B | The synthesis of tsiklomitsin and analogue thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-21 | — | — | CN | disclosed |
| EP-2682387-B1 | C7-fluoro substituted tetracycline compounds | TETRAPHASE PHARMACEUTICALS INC (US) | 2015-10-07 | — | — | EP | disclosed |
| US-9150541-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | SELDAR PHARMA INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-20150274643-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2015-10-01 | — | — | US | disclosed |
| EP-2149561-B1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC (US) | 2015-09-09 | — | — | EP | disclosed |
| CN-103665356-B | A kind of continuous processing prepares the method for polyester resin for powder coating | ZHANGJIAGANG BAOTIAN NEW MATERIAL TECHNOLOGY CO.,LTD. (CN) | 2015-08-26 | — | — | CN | disclosed |
| US-9115085-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| CN-103073455-B | Kcnq potassium channel agonist, Preparation Method And The Use that one class is novel | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-19 | — | — | CN | disclosed |
| EP-2406250-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2244712-B1 | IN VIVO STUDIES OF CRYSTALLINE FORMS OF MELOXICAM | THAR PHARMACEUTICALS INC (US) | 2015-08-05 | — | — | EP | disclosed |
| EP-2890673-A2 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-1930332-B1 | LUMINESCENT VARGULA LUCIFERIN SUBSTRATE AND PROCESS FOR PRODUCING THE SAME | NAT INST OF ADVANCED IND SCIEN (JP) | 2015-06-03 | — | — | EP | disclosed |
| CN-104684905-A | 6 '-phenyl-2, 2' -bipyridine-3-carboxylic acid derivatives having herbicidal activity | BAYER CROPSCIENCE AG | 2015-06-03 | — | — | CN | disclosed |
| CN-103030755-B | Method for synthesizing block polymers by reversible addition-fragmentation chain transfer free radical polymerization | UNIV FUDAN | 2015-04-22 | — | — | CN | disclosed |
| US-8975279-B2 | Amine salts of laquinimod | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2015-03-10 | — | — | US | disclosed |
| US-20150038529-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2015-02-05 | — | — | US | disclosed |
| US-8906887-B2 | C7-fluoro substituted tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8883823-B2 | Crystalline forms of a prolyl hydroxylase inhibitor | FIBROGEN, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140303202-A9 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2014-10-09 | — | — | US | disclosed |
| US-8796245-B2 | C7-fluoro substituted tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| CN-103193765-B | 1,8-naphthalene imide derivative and preparation method and application thereof | UNIV SOOCHOW | 2014-07-02 | — | — | CN | disclosed |
| CN-103877149-A | Phospholipid complex containing dracocephalum moldavica total flavonoids, self-emulsifying agent prepared from same and preparation method of phospholipid complex containing dracocephalum moldavica total flavonoids | XINJIANG INST OF METERIA MEDICA | 2014-06-25 | — | — | CN | disclosed |
| US-20140163238-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140128430-A1 | AMINE SALTS OF LAQUINIMOD | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2014-05-08 | — | — | US | disclosed |
| CN-103665356-A | Preparation method for thermoset saturate polyester resin used in powder coating according to continuous method | ZHANGJIAGANG POLYLAND NEW MATERIALS TECHNOLOGY CO LTD | 2014-03-26 | — | — | CN | disclosed |
| WO-2014036502-A2 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2014-03-06 | — | — | WO | disclosed |
| US-20140058100-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | SELDAR PHARMA INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140031230-A1 | AUXIN BIOSYNTHESIS INHIBITOR | Riken Public University Corporation Yokohama City University | 2014-01-30 | — | — | US | disclosed |
| US-20140024676-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN INC (US) | 2014-01-23 | — | — | US | disclosed |
| US-20140024675-A1 | CRYSTALLINE FORMS OF A PROLYL HYDROXYLASE INHIBITOR | FIBROGEN, INC. | 2014-01-23 | — | — | US | disclosed |
| EP-2248820-B1 | Universal supports for oligonucleotide synthesis | GLEN RES CORP (US) | 2014-01-08 | — | — | EP | disclosed |
| EP-2682387-A2 | C7-fluoro substituted tetracycline compounds | Tetraphase Pharmaceuticals, Inc. (US) | 2014-01-08 | — | — | EP | disclosed |
| US-8614221-B2 | Inhibitors of Akt activity | MERCK SHARP & DOHME CORP. (US) | 2013-12-24 | — | — | US | disclosed |
| EP-2668198-A1 | FGF RECEPTOR-ACTIVATING 3-O-ALKYL OLIGOSACCHARIDES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-12-04 | — | — | EP | disclosed |
| US-8598148-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-12-03 | — | — | US | disclosed |
| US-8501716-B2 | C7-fluoro substituted tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | disclosed |
| CN-103214409-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-24 | — | — | CN | disclosed |
| US-8486970-B2 | Tetrahydroisoquinolin-1-one derivative or salt thereof | SELDAR PHARMA INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486921-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-07-16 | — | — | US | disclosed |
| CN-103193765-A | 1,8-naphthalene imide derivative and preparation method and application thereof | UNIV SOOCHOW | 2013-07-10 | — | — | CN | disclosed |
| EP-2323972-B1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013092467-A1 | 7-AZAINDOLE INHIBITORS OF CRAC | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092463-A1 | 4-AZAINDOLE INHIBITORS OF CRAC | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092444-A1 | DIAZAINDOLE INHIBITORS OF CRAC | F. HOFFMANN-LA ROCHE AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-20130158049-A1 | 7-AZAINDOLE INHIBITORS OF CRAC | HOFFMANN-LA ROCHE INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158040-A1 | DIAZAINDOLE INHIBITORS OF CRAC | HOFFMANN-LA ROCHE INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158066-A1 | 4-AZAINDOLE INHIBITORS OF CRAC | HOFFMANN-LA ROCHE INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130109657-A1 | C7-Fluoro Substituted Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2013-05-02 | — | — | US | disclosed |
| CN-103073455-A | Novel KCNQ potassium channel agonist, and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2013-05-01 | — | — | CN | disclosed |
| US-20130090334-A1 | AZABENZOXAZINE DERIVATIVES AS CRAC MODULATORS | Hoffmann-La Roche Inc (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2013050270-A1 | BENZOXAZINE DERIVATIVES AS CRAC MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| US-20130090333-A1 | BENZOXAZINE DERIVATIVES AS CRAC MODULATORS | HOFFMANN-LA ROCHE INC. (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2013050341-A1 | AZABENZOXAZINE DERIVATIVES AS CRAC MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| EP-1404695-B1 | UNIVERSAL SUPPORTS FOR OLIGONUCLEOTIDE SYNTHESIS | GLEN RES CORP (US) | 2013-04-10 | — | — | EP | disclosed |
| CN-103030755-A | Method for synthesizing block polymers by reversible addition-fragmentation chain transfer free radical polymerization | UNIV FUDAN | 2013-04-10 | — | — | CN | disclosed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | disclosed |
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8389512-B2 | In vivo studies of crystalline forms of meloxicam | THAR PHARMACEUTICALS (US) | 2013-03-05 | — | — | US | disclosed |
| US-8343729-B2 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120302527-A1 | C7-Fluoro Substituted Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2012-11-29 | — | — | US | disclosed |
| EP-1852420-B1 | Indole compounds for treating respiratory disorders | ONO PHARMACEUTICAL CO (JP) | 2012-10-17 | — | — | EP | disclosed |
| CN-101768052-B | Method for preparing aromatic compound by catalytic hydrocracking of lignin | DALIAN CHEMICAL PHYSICS INST | 2012-09-26 | — | — | CN | disclosed |
| US-20120208788-A1 | Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2012-08-16 | — | — | US | disclosed |
| WO-2012101605-A1 | FGF RECEPTOR-ACTIVATING 3-O-ALKYL OLIGOSACCHARIDES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-08-02 | — | — | WO | disclosed |
| EP-2480529-A1 | INDOLE DERIVATIVES AS CRAC MODULATORS | F. Hoffmann-La Roche AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| CN-102584863-A | Metal complex of novel double piperidine derivative with symmetric structure | UNIV HEBEI TECHNOLOGY | 2012-07-18 | — | — | CN | disclosed |
| CN-101720315-B | Novel derivatives of psammaplin a, a method for their synthesis and their use for the prevention or treatment of cancer | CENTRE NAT RECH SCIENT | 2012-07-18 | — | — | CN | disclosed |
| EP-2470500-A2 | TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| US-20120149692-A1 | In Vivo Studies of Crystalline Forms of Meloxicam | THAR PHARMACEUTICALS (US) | 2012-06-14 | — | — | US | disclosed |
| CN-101475564-B | Novel preparation of losartan potassium | JIANGSU DEFENG CHEMICAL INDUSTRY CO LTD | 2012-05-23 | — | — | CN | disclosed |
| US-8173642-B2 | Aminodihydrothiazine derivatives | SHIONOGI & CO., LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| US-8124603-B2 | In vivo studies of crystalline forms of meloxicam | THAR PHARMACEUTICALS (US) | 2012-02-28 | — | — | US | disclosed |
| US-8115019-B2 | Cis-2, 6-disubstituted tetrahydropyran derivatives and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-02-14 | — | — | US | disclosed |
| US-20120004240-A1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME LLC | 2012-01-05 | — | — | US | disclosed |
| US-8076338-B2 | Such as 6-(4-phenylpiperazin-1-yl)-9H-purine; cell proliferation/differentiation | EXELIXIS, INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110288240-A1 | NOVEL PHOSPHAZENE-SUPPORTED CATALYST, NOVEL COMPOUND THEREOF AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2011-11-24 | — | — | US | disclosed |
| US-20110287459-A1 | Luciferin luminescent substrate of marine ostracod crustacean and method for production thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-11-24 | — | — | US | disclosed |
| EP-1775301-B1 | NOVEL SUPPORTED PHOSPHAZENE CATALYSTS, NOVEL COMPOUNDS FOR THE CATALYSTS, AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-7989621-B2 | Method for producing substituted imidazo[1,2-A]pyrazines of (s)-1-(3-(2-sec-butyl-6-(1h-indol-3-yl)-3-oxo-3,7-dihydroimadazo[1,2-a]pyrazin-8-yl)propyl)guanidine | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-08-02 | — | — | US | disclosed |
| EP-2323972-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | Tetraphase Pharmaceuticals, Inc. (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2011036130-A1 | INDOLE DERIVATIVES AS CRAC MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-31 | — | — | WO | disclosed |
| US-20110071150-A1 | INDOLE DERIVATIVES AS CRAC MODULATORS | ALAM MUZAFFAR | 2011-03-24 | — | — | US | disclosed |
| WO-2011025982-A2 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| US-20110021372-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2011-01-27 | — | — | US | disclosed |
| US-20110009371-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-01-13 | — | — | US | disclosed |
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-11-25 | — | — | US | disclosed |
| EP-2248820-A1 | Universal supports for oligonucleotide synthesis | Glen Research Corporation (US) | 2010-11-10 | — | — | EP | disclosed |
| EP-2244712-A1 | IN VIVO STUDIES OF CRYSTALLINE FORMS OF MELOXICAM | Thar Pharmaceuticals Inc. (US) | 2010-11-03 | — | — | EP | disclosed |
| US-7807842-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-10-05 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100227866-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-09 | — | — | US | disclosed |
| US-7776369-B2 | lignan extract comprising a lignan complex including secoisolariciresinol diglucoside;wherein the lignan extract is substantially free of cyanogenic glycosides as determined by measuring free cyanides; use in treating cancer, diabetes, hypertension, lupus, and atherosclerosis | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776533-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2010-08-17 | — | — | US | disclosed |
| CN-101768052-A | Method for preparing aromatic compound by catalytic hydrocracking of lignin | DALIAN CHEMICAL PHYSICS INST | 2010-07-07 | — | — | CN | disclosed |
| CN-101720315-A | Novel derivatives of psammaplin a, a method for their synthesis and their use for the prevention or treatment of cancer | CENTRE NAT RECH SCIENT | 2010-06-02 | — | — | CN | disclosed |
| US-7728023-B2 | Indole compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20100130451-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2010-05-27 | — | — | US | disclosed |
| EP-1773330-B1 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK SHARP & DOHME (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20100113550-A1 | New Crystal Forms | BIAL - PORTELA AND CA, S.A. (PT) | 2010-05-06 | — | — | US | disclosed |
| US-20100105671-A1 | C7-fluoro substituted tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2010-04-29 | — | — | US | disclosed |
| CN-101648945-A | Synthesis of important irbesartan intermediate | JIANGSU DEFENG PHARMACEUTICAL | 2010-02-17 | — | — | CN | disclosed |
| WO-2010017470-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-2149561-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| US-7655643-B2 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2010-02-02 | — | — | US | disclosed |
| US-20100009381-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | Life Technologies Corporation (US) | 2010-01-14 | — | — | US | disclosed |
| US-7635698-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-22 | — | — | US | disclosed |
| EP-2130544-A2 | Processes for obtaining lignan extracts and compositions containing the lignan extracts | Archer-Daniels-Midland Company (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7625938-B2 | Substituted pyrazoles, compositions containing such compounds and methods of use | MERCK & CO., INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20090209770-A1 | CIS-2, 6-DISUBSTITUTED TETRAHYDROPYRAN DERIVATIVES AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-08-20 | — | — | US | disclosed |
| US-20090203680-A1 | In vivo studies of crystalline forms of meloxicam | THAR PHARMACEUTICALS (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2009094155-A1 | IN VIVO STUDIES OF CRYSTALLINE FORMS OF MELOXICAM | THAR PHARMACEUTICALS (US) | 2009-07-30 | — | — | WO | disclosed |
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1753713-A4 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2009-07-08 | — | — | EP | disclosed |
| CN-101475564-A | Novel preparation of losartan potassium | JIANGSU DEFENG CHEMICAL INDUST (CN) | 2009-07-08 | — | — | CN | disclosed |
| US-7553845-B2 | Substituted indolizine 1,2,3,6,7,8 derivatives, FGFs inhibitors, a method for the preparation thereof and pharmaceutical compositions containing said derivatives | SANOFI-AVENTIS (FR) | 2009-06-30 | — | — | US | disclosed |
| US-20090136974-A1 | Luciferin Luminescent Substrate of Marine Ostracod Crustacean and Method for Production Thereof | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE TECHNOLOGY (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20090082560-A1 | AMINODIHYDROTHIAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| US-7491817-B2 | Universal supports for oligonucleotide synthesis | GLEN RESEARCH CORPORATION (US) | 2009-02-17 | — | — | US | disclosed |
| US-20090029981-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | NOVARTIS AG (CH) | 2009-01-29 | — | — | US | disclosed |
| EP-2018862-A1 | Substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2009-01-28 | — | — | EP | disclosed |
| EP-2016044-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20080318767-A1 | Novel Phosphazene-Supported Catalyst, Novel Compound Thereof and Use Thereof | MITSUI CHEMICALS, INC. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-20080317888-A1 | PROCESS FOR OBTAINING LIGNANS | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2008-12-25 | — | — | US | disclosed |
| US-7465719-B2 | Carbamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| CN-101316603-A | Processes for obtaining lignan extracts and compositions containing the lignan extracts | ARCHER DANIELS MIDLAND CO (US) | 2008-12-03 | — | — | CN | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
| US-7445894-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| CN-101291912-A | Pyrazole derivatives, compositions containing such compounds and methods of use | MERCK & CO INC (US) | 2008-10-22 | — | — | CN | disclosed |
| EP-1973555-A2 | PROCESSES FOR OBTAINING LIGNAN EXTRACTS AND COMPOSITIONS CONTAINING THE LIGNAN EXTRACTS | Archer-Daniels-Midland Company (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1973903-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | Speedel Experimenta AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| CN-101273041-A | Fluorescent substance luminescent substrate for marine firefly and manufacturing method thereof | NAT INST OF ADVANCED IND SCIEN (JP) | 2008-09-24 | — | — | CN | disclosed |
| US-20080206885-A1 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2008-08-28 | — | — | US | disclosed |
| US-20080188532-A1 | Indole Compound and Use Thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-7407676-B2 | Lignan extracts and compositions including the lignan extracts | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2008-08-05 | — | — | US | disclosed |
| EP-1940799-A1 | PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1930332-A1 | LUMINESCENT VARGULA LUCIFERIN SUBSTRATE AND PROCESS FOR PRODUCING THE SAME | National Institute Of Advanced Industrial Science and Technology (JP) | 2008-06-11 | — | — | EP | disclosed |
| CN-101184996-A | Electrochemical detection method | INVERNESS MEDICAL SWITZERLAND (CH) | 2008-05-21 | — | — | CN | disclosed |
| US-20080108620-A1 | Substituted Pyrazoles, Compositions Containing such Compounds and Methods of Use | MERCK & CO., INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-7368472-B2 | 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system | H. LUNDBECK A/S (DK) | 2008-05-06 | — | — | US | disclosed |
| WO-2007117639-A9 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | HARVARD COLLEGE (US) | 2008-04-17 | — | — | WO | disclosed |
| EP-1910337-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080076774-A1 | Kinase Modulators and Methods of Use | EXELIXIS, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-20080044804-A1 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES | INVITROGEN CORPORATION (US) | 2008-02-21 | — | — | US | disclosed |
| CN-101128424-A | Indole compound and use thereof | ONO PHARMACEUTICAL CO (JP) | 2008-02-20 | — | — | CN | disclosed |
| US-20080021071-A1 | 3-{4-(Pyridin-3-Yl) Phenyl}-5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents | ASTRAZENECA AB (SE) | 2008-01-24 | — | — | US | disclosed |
| EP-1852420-A1 | INDOLE COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007117639-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-10-18 | — | — | WO | disclosed |
| CN-101027279-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE (US) | 2007-08-29 | — | — | CN | disclosed |
| US-7261991-B2 | Image forming method and image forming apparatus | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-08-28 | — | — | US | disclosed |
| WO-2007082907-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-07-26 | — | — | WO | disclosed |
| CN-1993124-A | Substituted pyrazoles, compositions containing such compounds and methods of use | MERCK & CO INC (US) | 2007-07-04 | — | — | CN | disclosed |
| US-20070141178-A1 | Processes for Obtaining Lignan Extracts and Compositions Containing the Lignan Extracts | ARCHER DANIELS MIDLAND COMPANY | 2007-06-21 | — | — | US | disclosed |
| WO-2007065023-A2 | PROCESSES FOR OBTAINING LIGNAN EXTRACTS AND COMPOSITIONS CONTAINING THE LIGNAN EXTRACTS | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007016545-A9 | POROUS MATERIALS HAVING MULTI-SIZE GEOMETRIES | UNIV MICHIGAN (US) | 2007-06-07 | — | — | WO | disclosed |
| CN-1964947-A | Pyrazole derivatives, compositions containing the same and methods of use thereof | MERCK & CO INC (US) | 2007-05-16 | — | — | CN | disclosed |
| US-20070099885-A1 | Antibacterial macrocycles with substituted biphenyl | AICURIS GMBH & CO. KG (DE) | 2007-05-03 | — | — | US | disclosed |
| WO-2007047676-A1 | PYRAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070088070-A1 | Pyrazole derivatives, compositions containing such compounds and methods of use | PARMEE EMMA R | 2007-04-19 | — | — | US | disclosed |
| EP-1775301-A1 | NOVEL SUPPORTED PHOSPHAZENE CATALYSTS, NOVEL COMPOUNDS FOR THE CATALYSTS, AND USE THEREOF | Mitsui Chemicals Polyurethanes, Inc. (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1578740-B1 | 1,2,4-TRIAMINOBENZENE DERIVATIVES USEFUL FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM | LUNDBECK & CO AS H (DK) | 2007-03-21 | — | — | EP | disclosed |
| US-20070054304-A1 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES | INVITROGEN CORPORATION (US) | 2007-03-08 | — | — | US | disclosed |
| EP-1753713-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | The President and Fellows of Harvard College (US) | 2007-02-21 | — | — | EP | disclosed |
| US-20070036844-A1 | Porous materials having multi-size geometries | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2007-02-15 | — | — | US | disclosed |
| EP-1750727-A2 | KINASE MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2007016545-A2 | POROUS MATERIALS HAVING MULTI-SIZE GEOMETRIES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-02-08 | — | — | WO | disclosed |
| US-7160992-B2 | Amino-modified polysaccharides and methods of generating and using same | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2007-01-09 | — | — | US | disclosed |
| US-20070004890-A1 | N-vinylformamide derivatives, polymers formed therefrom and synthesis thereof | PITTSBURGH- OF THE COMMONWEALTH SYSTEMS OF HIGHER EDUCATION, UNIVERSITY OF | 2007-01-04 | — | — | US | disclosed |
| WO-2006138744-A2 | HETEROARYL DERIVATIVES FOR TREATING VIRUSES | GENELABS TECHNOLOGIES, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060293320-A1 | Heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2006-12-28 | — | — | US | disclosed |
| US-7135598-B2 | N-vinylformamide derivatives, polymers formed therefrom and synthesis thereof | UNIVERSITY OF PITTSBURGH (US) | 2006-11-14 | — | — | US | disclosed |
| US-20060229236-A1 | Cyclic tetrapeptide compound and use thereof | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060229316-A1 | Novel antiinfective compounds, process for their preparation and pharmaceutical compositions containing them | CADILA HEALTHCARE LIMITED (IN) | 2006-10-12 | — | — | US | disclosed |
| US-20060199962-A1 | Substituted indolizine 1,2,3,6,7,8 derivatives, FGFs inhibitors, a method for the preparation thereof and pharmaceutical compositions containing said derivatives | SANOFI-AVENTIS (FR) | 2006-09-07 | — | — | US | disclosed |
| US-7102005-B2 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-7098234-B2 | Indole derivatives, process for preparation of the same and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-29 | — | — | US | disclosed |
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
| US-7030145-B2 | Pyridinyl derivatives for the treatment of depression | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060058282-A1 | Carbamic acid compounds comprising an ester or ketone linkage as hdac inhibitors | TOPOTARGET UK LIMITED (GB) | 2006-03-16 | — | — | US | disclosed |
| CN-1244573-C | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2006-03-08 | — | — | CN | disclosed |
| US-20060040199-A1 | Image forming method and image forming apparatus | KONICA MINOLTA HOLDINGS, INC. (JP) | 2006-02-23 | — | — | US | disclosed |
| US-20060014822-A1 | 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system | H. LUNDBECK A/S (DK) | 2006-01-19 | — | — | US | disclosed |
| US-20050282787-A1 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2005-12-22 | — | — | US | disclosed |
| WO-2005117909-A2 | KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005112945-A2 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050250116-A1 | Universal supports for oligonucleotide synthesis | GLEN RESEARCH CORPORATION (US) | 2005-11-10 | — | — | US | disclosed |
| WO-2005105257-A1 | CHROMATOGRAPHIC STATIONARY PHASE FOR SEPARATION OF CYCLODEXTRINE AND DERIVATIVES THEREOF | CHIROQUEST KIRÁLIS TECHNOLÓGIÁKAT FEJLESZTÖ KFT. (HU) | 2005-11-10 | — | — | WO | disclosed |
| EP-1583736-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN ESTER OR KETONE LINKAGE AS HDAC INHIBITORS | TopoTarget UK Limited (GB) | 2005-10-12 | — | — | EP | disclosed |
| EP-1578740-A1 | 1,2,4-TRIAMINOBENZENE DERIVATIVES USEFUL FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM | H. Lundbeck A/S (DK) | 2005-09-28 | — | — | EP | disclosed |
| EP-0882733-B1 | Acylating agent and a method of producing thereof | ENSUIKO SUGAR REFINING (JP) | 2005-09-14 | — | — | EP | disclosed |
| CN-1665790-A | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES INC (US) | 2005-09-07 | — | — | CN | disclosed |
| EP-1558341-A2 | TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Paratek Pharmaceuticals, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-6919362-B2 | Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-07-19 | — | — | US | disclosed |
| EP-1546118-A2 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES | Molecular Probes Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2005047901-A2 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION PHOSPHORYLATED MOLECULES | MOLECULAR PROBES, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | disclosed |
| US-20050014197-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2005-01-20 | — | — | US | disclosed |
| US-20040229265-A1 | Amino-modified polysaccharides and methods of generating and using same | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2004-11-18 | — | — | US | disclosed |
| US-20040224902-A1 | Process for obtaining lignans | SHUKLA RISHI (US) | 2004-11-11 | — | — | US | disclosed |
| US-20040209917-A1 | Pyridinyl derivatives for the treatment of depression | HARTZ RICHARD A (US) | 2004-10-21 | — | — | US | disclosed |
| US-20040192680-A1 | Novel amides that activate soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-09-30 | — | — | US | disclosed |
| US-20040186151-A1 | Substituted azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. | 2004-09-23 | — | — | US | disclosed |
| EP-1458746-A2 | CYCLIC TETRAPEPTIDE COMPOUND AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040180885-A1 | Indole derivatives, process for preparation of the same and use thereof | ONO PHARMACEUTICAL CO., LTD. | 2004-09-16 | — | — | US | disclosed |
| US-20040171034-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2004-09-02 | — | — | US | disclosed |
| WO-2004065354-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN ESTER OR KETONE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2004-08-05 | — | — | WO | disclosed |
| US-6770754-B2 | FUNCTIONALIZED POLYMERIC OR SILICA BASE MATERIAL; DO NOT INCLUDE A PRE-ATTACHED NUCLEOSIDE, AND THEREFORE CAN BE USED UNIVERSALLY FOR ANY NA OR RNA SYNTHESIS; FAST CLEAVAGE AND DEPHOSPHORYLATION AT RELATIVELY LOW TEMPERATURES | GLEN RESEARCH COPORATION | 2004-08-03 | — | — | US | disclosed |
| US-6767565-B2 | RECOVERING LIGNANS FROM PLANTS; OBTAIN PLANT BIOMASS, EXPOSE TO EXTRACTION SOLVENT, SEPARATE SOLID PLANT MATERIAL, REMOVE MICROORGANISM FROM EXTRACTION SOLUTION, RECOVER LIGNAN | ARCHER DANIELS MIDLAND COMPANY | 2004-07-27 | — | — | US | disclosed |
| WO-2004058739-A1 | 1,2,4-TRIAMINOBENZENE DERIVATIVES USEFUL FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM | H. LUNDBECK A/S (DK) | 2004-07-15 | — | — | WO | disclosed |
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-07-01 | — | — | US | disclosed |
| US-20040121994-A1 | Novel amides that activate soluble guanylate cyclase | ABBOTT LABORATORIES | 2004-06-24 | — | — | US | disclosed |
| WO-2004022524-A9 | N-VINYLFORMAMIDE DERIVATIVES, POLYMERS FORMED THEREFROM AND SYNTHESIS THEREOF | UNIV PITTSBURGH (US) | 2004-06-24 | — | — | WO | disclosed |
| US-6743793-B2 | DP RECEPTOR ANTAGONIST; PROSTAGLANDIN D | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-06-01 | — | — | US | disclosed |
| WO-2004041209-A2 | TRANSCRIPTION FACTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PARATEK PHARMACEUTICALS, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| WO-2004042347-A2 | COMPOSITIONS AND METHODS FOR DETECTION AND ISOLATION OF PHOSPHORYLATED MOLECULES | MOLECULAR PROBES, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-1022284-B1 | TAXOID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | BIO RES CORP OF YOKOHAMA (JP) | 2004-05-12 | — | — | EP | disclosed |
| WO-2004022524-A3 | N-VINYLFORMAMIDE DERIVATIVES, POLYMERS FORMED THEREFROM AND SYNTHESIS THEREOF | UNIV PITTSBURGH (US) | 2004-05-06 | — | — | WO | disclosed |
| US-6727245-B2 | 4-(HETERO)ARYL-3-OXO-3,4-DIHYDROPYRIDO(2,3-B)PYRAZINE DERIVATIVES; PROPHYLACTIC OR THERAPEUTIC TREATMENT OF PHOSPHODIESTERASE IV AND TUMOR NECROSIS FACTOR MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-04-27 | — | — | US | disclosed |
| EP-1404695-A2 | UNIVERSAL SUPPORTS FOR OLIGONUCLEOTIDE SYNTHESIS | Glen Research Corporation (US) | 2004-04-07 | — | — | EP | disclosed |
| US-6710205-B2 | ANTIALLERGENS; ANTICANCER AGENTS; AUTOIMMUNE DISEASES; BONE DISORDERS; RHEUMATIC DISEASES; ANTIULCER AGENTS; SKIN DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| WO-2004022524-A2 | N-VINYLFORMAMIDE DERIVATIVES, POLYMERS FORMED THEREFROM AND SYNTHESIS THEREOF | UNIVERSITY OF PITTSBURGH (US) | 2004-03-18 | — | — | WO | disclosed |
| EP-0882732-B1 | Taxoid derivative and method of producing thereof | ENSUIKO SUGARREFINING COMPANY (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-20040038306-A1 | Compositions and methods for detection and isolation of phosphorylated molecules | MOLECULAR PROBES, INC. | 2004-02-26 | — | — | US | disclosed |
| EP-1373287-A1 | PROCESS FOR OBTAINING LIGNAN, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Shukla, Rishi (US) | 2004-01-02 | — | — | EP | disclosed |
| CN-1445222-A | Benzofuran category compound, its preparing method and usage | SHANGHAI MEDICATION INST CHINE (CN) | 2003-10-01 | — | — | CN | disclosed |
| US-20030176400-A1 | Indole derivatives, process for preparation of the same and use thereof | ONO PHARMACEUTICALS CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1119529-B1 | CHEMICAL CONSTRUCTS | GLAXO GROUP LTD (GB) | 2003-09-17 | — | — | EP | disclosed |
| US-6605626-B2 | Benzamide inhibitors of factor Xa | ELI LILLY AND COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-6596751-B2 | An insulin resistance improving agent, hypoglycemic agent, immunoregulatory agent, aldose reductase inhibitor, 5-lipoxygenase inhibitor, peroxidized lipid production suppressor, PPAR. activator, leukotriene antagonist, adipose | SANKYO COMPANY LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| WO-2003057722-A2 | CYCLIC TETRAPEPTIDE COMPOUND AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-19 | — | — | US | disclosed |
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1307426-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | Bayer Aktiengesellschaft (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-6551682-B1 | Proper tracking error signals to be adapted to high density information recording and has various characteristics | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20030069294-A1 | Alpha-substituted carboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-04-10 | — | — | US | disclosed |
| WO-2003027108-A1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS HYPOGLYCAEMIC AND HYPOLIPIDEMIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2003-04-03 | — | — | WO | disclosed |
| US-20030055227-A1 | Process for obtaining lignan | ARCHER-DANIELS-MIDLAND COMPANY | 2003-03-20 | — | — | US | disclosed |
| US-20030040533-A1 | Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2003-02-27 | — | — | US | disclosed |
| EP-0770079-B1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-02-12 | — | — | EP | disclosed |
| CN-1390139-A | Oncolytic combinations for the treatment of cancer | LILLY CO ELI (US) | 2003-01-08 | — | — | CN | disclosed |
| EP-1258473-A1 | BENZOIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| EP-1252150-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2002-10-30 | — | — | EP | disclosed |
| CN-1374863-A | Bicyclic antagonists selective for the alpha beta integrin | WHAE S INC (US) | 2002-10-16 | — | — | CN | disclosed |
| WO-2002077003-A1 | PROCESS FOR OBTAINING LIGNAN, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20020137855-A1 | Universal supports for oligonucleotide synthesis | GLEN RESEARCH CORPORATION (US) | 2002-09-26 | — | — | US | disclosed |
| US-20020120007-A1 | Benzamide inhibitors of factor Xa | BEIGHT DOUGLAS WADE (US) | 2002-08-29 | — | — | US | disclosed |
| US-20020107251-A1 | Heterobicyclic derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-08 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
| US-6426345-B1 | PHOSPHODIESTERASE INHIBITORS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-30 | — | — | US | disclosed |
| EP-1218319-A1 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2002-07-03 | — | — | EP | disclosed |
| WO-2002044398-A2 | UNIVERSAL SUPPORTS FOR OLIGONUCLEOTIDE SYNTHESIS | GLEN RESEARCH CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-1198231-A1 | BICYCLIC ANTAGONISTS SELECTIVE FOR THE(ALPHA)V(BETA)3 INTEGRIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-04-24 | — | — | EP | disclosed |
| EP-1187825-A1 | THIOPHENE INTEGRIN INHIBITORS | Shire Biochem Inc. (CA) | 2002-03-20 | — | — | EP | disclosed |
| WO-2002012169-A1 | AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-02-14 | — | — | WO | disclosed |
| US-6313122-B1 | AS INHIBITORS OF FACTOR XA AND ARE USED AS ANTICOAGULANTS IN MAMMALS | ELI LILLY AND COMPANY | 2001-11-06 | — | — | US | disclosed |
| US-6306893-B1 | PACLITAL, DOCETAXEL AND DEACETYLBACCATIN III TO WHICH GALACTOSE OR MANNOSE IS LINKED THROUGH A GLYCOLATE AND A SPACER | ENSUIKO SUGAR REFINING COMPANY, LTD (JP) | 2001-10-23 | — | — | US | disclosed |
| US-6274620-B1 | 2-BENZENESULFONYLAMINO-3-((5-BROMO-THIOPHENE-2-CARBONYL)-AMINO )PROPIONIC ACID-TERT-BUTYL ESTERS AS ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; OSTEOPOROSIS, RESTENOSIS, AND OCULAR NEOVASCULARIZATION | BIOCHEM PHARMA INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-2001057002-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2001-08-09 | — | — | WO | disclosed |
| EP-1119529-A2 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2001025171-A1 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2001-04-12 | — | — | WO | disclosed |
| WO-2001007036-A1 | BICYCLIC ANTAGONISTS SELECTIVE FOR THE αvβ3 INTEGRIN | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-01 | — | — | WO | disclosed |
| CN-1279669-A | Aromatic sulfone hydroxamic acid metalloprotease inhibitors | SEARLE & CO (US) | 2001-01-10 | — | — | CN | disclosed |
| WO-2000075129-A1 | THIOPHENE INTEGRIN INHIBITORS | SHIRE BIOCHEM INC. (CA) | 2000-12-14 | — | — | WO | disclosed |
| US-6160124-A | Method for treating or preventing arteriosclerosis | JAPAN TOBACCO INC. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-1022284-A1 | TAXOID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Bio Research Corporation of Yokohama (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-6075132-A | SACCHARIDE MOIETY BONDED TO DERIVATIVE VIA A SPACER; FOR IMPROVED WATER SOLUBILTY FOR INJECTABLE CHOLAGOGIC AGENTS | BIO RESEARCH CORPORATION OF YOKOHAMA (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0719767-B1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-6057343-A | HAVE SUPERIOR HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIONS AND ARE USEFUL FOR THE TREATMENT OF DIABETES AND THE COMPLICATIONS THEREOF, AS WELL AS THERAPEUTIC AGENTS FOR RELATED DISEASES SUCH AS HYPERLIPIDEMIA | JAPAN TOBACCO, INC. (JP) | 2000-05-02 | — | — | US | disclosed |
| WO-2000020357-A2 | CHEMICAL CONSTRUCTS | GLAXO GROUP LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
| US-6037359-A | ARTERIOSCLEROSIS PREVENTION; ANTIDIABETIC AGENTS; ANTILIPEMIC AND HYPOGLYCEMIC AGENTS | JAPAN TOBACCO, INC. (JP) | 2000-03-14 | — | — | US | disclosed |
| US-5981500-A | Antiparasitic agents related to the milbemycins and avermectins | PFIZER INC. (US) | 1999-11-09 | — | — | US | disclosed |
| US-5939445-A | ISOXAZOLIDINEDIONES COMPOUNDS AS HYPOGLYCEMIC AGENTS AND TREATMENT OF ARTERIOSCLEROSIS | JAPAN TOBACCO, INC. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0920867-A1 | Pyrido[2,3-a]pyrazine derivatives as PDE-IV and TNF inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0684242-B1 | ISOXAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | JAPAN TOBACCO INC (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5854408-A | Process for acylating the 1-position of saccharides | ENSUIKO SUGAR REFINING CO., LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0882733-A1 | Acylating agent and a method of producing thereof | Ensuiko Sugar Refining Company, Limited (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882732-A1 | Taxoid derivative and method of producing thereof | Ensuiko Sugar Refining Company, Limited (JP) | 1998-12-09 | — | — | EP | disclosed |
| JP-H10195555-A | SEPARATING MATERIAL FOR GERMANIUM | AGENCY OF IND SCIENCE & TECHNOL | 1998-07-28 | — | — | JP | disclosed |
| US-5773227-A | CHELATE COMPOUNDS, FLUORESCENT INDICATOR AND TARGET PEPTIDES | MOLECULAR PROBES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5773592-A | COMPRISES A CHEMILUMINESCENT MOIETY, A PHOTOCHROMIC MOIETY AND A BIOLOGICALLY ACTIVE AGENT CAPABLE OF BEING RELEASED | MILLS RANDELL LEE (US) | 1998-06-30 | — | — | US | disclosed |
| US-5767297-A | WATER SOLUBILITY; TAXOL DERIVATIVE COMBINED WITH A SUGAR | ENSUIKO SUGAR REFINING CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5750508-A | Sialic acid/fucose based medicaments | GLYCOMED INCORPORATED (US) | 1998-05-12 | — | — | US | disclosed |
| US-5728720-A | HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; TREATMENT OF DIABETES | JAPAN TOBACCO INC. (JP) | 1998-03-17 | — | — | US | disclosed |
| US-5688818-A | ENZYME INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5679321-A | Sialic acid/fucose based medicaments | GLYCOMED INCORPORATED (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0754242-A4 | OLIGONUCLEOTIDE N3'-m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS INC (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0579614-B1 | IMIDAZOACRIDINES AND THEIR ANTINEOPLASTIC USE | BRITISH TECH GROUP (GB) | 1997-05-28 | — | — | EP | disclosed |
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0770079-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| EP-0754242-A1 | OLIGONUCLEOTIDE N3'$m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS, INC. (US) | 1997-01-22 | — | — | EP | disclosed |
| EP-0719767-A1 | SUCCINAMIC ACID COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5512648-A | IMMUNOASSAY | Sparrow, James (US) | 1996-04-30 | — | — | US | disclosed |
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0492667-B1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | GREEN CROSS CORP (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |
| WO-1996001825-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-01-25 | — | — | WO | disclosed |
| US-5478850-A | Treating hyperglycemia, hyperlipidemia, hypertension | BEECHAM GROUP PLC (GB) | 1995-12-26 | — | — | US | disclosed |
| EP-0684242-A1 | ISOXAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | JAPAN TOBACCO INC. (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0677054-A1 | NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS | PFIZER INC. (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1995025814-A1 | OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES | LYNX THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | disclosed |
| US-5453517-A | Covalently attached to fluorophores and/or polymers; detoxify excess metals, in vitro buffers, optical indicators of ionic transients | MOLECULAR PROBES, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5426244-A | Para-selective; reacting a phenol with hydrogen peroxide in presence of crystalline titanosilicate catalyst and cyclic ether | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0507008-B1 | Lithographic printing plate based on a resin comprising aryldiazosulfonates | AGFA GEVAERT NV (BE) | 1995-06-07 | — | — | EP | disclosed |
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| WO-1994015944-A1 | NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS | PFIZER LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |
| US-5310881-A | Reaction product of mucopolysaccharides and enzymes, sustained release, drugs | SEIKAGAKU CORPORATION (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5296572-A | Mixing unsaturated or alkenoylamine with dimethylacrylamide, crosslinker, water, adding emulsifier, adding organic phase, agitating, adding initiator, adjusting pH, adding promoter, polymerizing, isolating polyamide beads | Sparrow, James (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0579614-A1 | IMIDAZOACRIDINES AND THEIR ANTINEOPLASTIC USE. | BRITISH TECH GROUP (GB) | 1994-01-26 | — | — | EP | disclosed |
| US-5264567-A | GM3 analogous compound | MECT CORPORATION (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5252571-A | 1,4-benzothiazine-2-acetic acid derivatives | SAPPORO BREWERIES LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0555249-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| EP-0275005-B1 | COMPLEX COMPOUNDS OF BIOFLAVONOIDS WITH PHOSPHOLIPIDS, THEIR PREPARATION AND USE, AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM | INDENA S.p.A. (IT) | 1993-08-11 | — | — | EP | disclosed |
| US-5231100-A | ANTINEOPLASTIC MODIFIED IMIDAZOACRIDINES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-07-27 | — | — | US | disclosed |
| CN-1020098-C | Production for thiolactam-N-acetic acid derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-03-17 | — | — | CN | disclosed |
| EP-0479780-A4 | HOMOGENEOUS CATALYST FORMULATIONS FOR METHANOL PRODUCTION | — | 1992-11-04 | — | — | EP | disclosed |
| EP-0507008-A1 | Lithographic printing plate based on a resin comprising aryldiazosulfonates | AGFA-GEVAERT N.V. (BE) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992015583-A1 | IMIDAZOACRIDINES AND THEIR ANTINEOPLASTIC USE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1992-09-17 | — | — | WO | disclosed |
| EP-0502668-A1 | Imidazoacridines and their antineoplastic use | BTG INTERNATIONAL LIMITED (GB) | 1992-09-09 | — | — | EP | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0492667-A1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | THE GREEN CROSS CORPORATION (JP) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992007839-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |
| EP-0482584-A2 | GM3 analogous compound and preparation method thereof | MECT CORPORATION (JP) | 1992-04-29 | — | — | EP | disclosed |
| EP-0479780-A1 | HOMOGENEOUS CATALYST FORMULATIONS FOR METHANOL PRODUCTION. | US ENERGY (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0454898-A1 | Glycosaminoglycan-modified protein, process for the production of this protein, use and pharmaceutical compositions containing the same | SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-5043323-A | Complex compounds of bioflavonoids with phospholipids, their preparation and use, and pharmaceutical and cosmetic compositions containing them | INDENA S.P.A. (IT) | 1991-08-27 | — | — | US | disclosed |
| US-4992480-A | Mixture of metal carbonyl and alkoxide | ASSOCIATED UNIVERSITIES, INC. (US) | 1991-02-12 | — | — | US | disclosed |
| WO-1991000144-A1 | HOMOGENEOUS CATALYST FORMULATIONS FOR METHANOL PRODUCTION | UNITED STATES DEPARTMENT OF ENERGY (US) | 1991-01-10 | — | — | WO | disclosed |
| EP-0243018-B1 | THIOLACTAM-N-ACETIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0098865-B1 | PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1989-03-01 | — | — | EP | disclosed |
| EP-0292365-A2 | 4-Amino-5,8-quinazolindione derivatives, process for their preparation and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1988-11-23 | — | — | EP | disclosed |
| WO-1988008841-A1 | AMINO-4 QUINAZOLINEDIONE-5,8 DERIVATIVES, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-11-17 | — | — | WO | disclosed |
| US-4771050-A | ALDOSE REDUCTASE INHIBITOR, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| US-4760180-A | N-terminally substituted dipeptide amides | G. D. SEARLE & CO. (US) | 1988-07-26 | — | — | US | disclosed |
| EP-0275005-A2 | Complex compounds of bioflavonoids with phospholipids, their preparation and use, and pharmaceutical and cosmetic compositions containing them | INDENA S.p.A. (IT) | 1988-07-20 | — | — | EP | disclosed |
| CN-87102891-A | Production and use of sulfurized lactam-N-acetic acid derivatives | — | 1987-11-04 | — | — | CN | disclosed |
| EP-0243018-A1 | Thiolactam-N-acetic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| US-4661595-A | TREATING KETONE COMPOUND WITH S OR SULFIDE | SANDOZ LTD. (CH) | 1987-04-28 | — | — | US | disclosed |
| EP-0213481-A2 | N-terminally substituted dipeptide amides No. 2 | G.D. Searle & Co. (US) | 1987-03-11 | — | — | EP | disclosed |
| EP-0098865-A4 | PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS. | RESEARCH CORP (US) | 1986-11-20 | — | — | EP | disclosed |
| US-4601854-A | Process for the production of prednisone 17.21-diacylates | ROUSSEL UCLAF (FR) | 1986-07-22 | — | — | US | disclosed |
| US-4595592-A | Process for obtaining laxative compounds from senna drugs | DR. MADAUS & CO. (DE) | 1986-06-17 | — | — | US | disclosed |
| US-4587203-A | USING A DEVELOPMENT SOLVENT AND RINSING NONSOLVENT; SILANE COUPLING INTERLAYER; DIMENSIONAL STABILITY AND SHARPNESS OF IMAGE | HUGHES AIRCRAFT COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4581167-A | DIPEPTIDE INTERMEDIATE | RESEARCH CORPORATION (US) | 1986-04-08 | — | — | US | disclosed |
| US-4565863-A | ANTITUMOR AGENTS, SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0037635-B1 | THIOPYRYLIUM SENSITIZING DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0056692-B1 | 7-SUBSTITUTED CAMPTOTHECIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4535054-A | IRRADIATION TO GIVE NEGATIVE PATTERN IMAGE, DEVELOPMENT BY DISSOLUING UNEXPOSED POLYMER WITH SOLVENT AND RINSING | HUGHES AIRCRAFT COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| US-4508657-A | Peptide synthesis and amino acid blocking agents | RESEARCH CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| US-4486602-A | GLUCOSIDASE UNHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-12-04 | — | — | US | disclosed |
| EP-0049981-B1 | VALIENAMINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-07-25 | — | — | EP | disclosed |
| EP-0098865-A1 | PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS. | RESEARCH CORP (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4399276-A | 7-Substituted camptothecin derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1983-08-16 | — | — | US | disclosed |
| WO-1983002612-A1 | THIOPYRYLIUM SENSITIZING DYES | KATRITZKY, ALAN, R. | 1983-08-04 | — | — | WO | disclosed |
| WO-1983002448-A1 | PEPTIDE SYNTHESIS AND AMINO ACID BLOCKING AGENTS | RESEARCH CORP (US) | 1983-07-21 | — | — | WO | disclosed |
| US-4394519-A | N-(INDENYLMETHOXYCARBONYL) AMINO ACIDS | RESEARCH CORPORATION (US) | 1983-07-19 | — | — | US | disclosed |
| US-4384034-A | Thiopyrylium dye sensitized photoconductive materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
| US-4368329-A | COUPLING THIAPYRYLIUM SALT WITH AN AMINE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| US-RE31071-E | 6-Aza-3H-1,4-benzodiazepines | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1982-11-02 | — | — | US | disclosed |
| EP-0056692-A1 | 7-Substituted camptothecin derivatives and process for their preparation | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1982-07-28 | — | — | EP | disclosed |
| EP-0049981-A1 | Valienamine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-04-21 | — | — | EP | disclosed |
| EP-0004793-B1 | 2-NITRO AMINOPYRIMIDONE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE 2-AMINOPYRIMIDONE DERIVATIVES WHICH HAVE HISTAMINE H2-ANTAGONIST ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-12-30 | — | — | EP | disclosed |
| EP-0003677-B1 | PYRIMIDONES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-11 | — | — | EP | disclosed |
| EP-0037635-A1 | Thiopyrylium sensitizing dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-10-14 | — | — | EP | disclosed |
| US-4263214-A | REACTING WITH DIALKYLAMINO SULFUR TRIFLUORIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4230627-A | CALCIUM METABOLISM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4229357-A | Fluorovitamin D compounds and processes for their preparation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4229358-A | Fluorovitamin D compounds and processes for their preparation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4226787-A | Fluorovitamin D compounds and processes for their preparation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4224230-A | STIMULATE INTESTINAL CALCIUM TRANSPORT AND BONE MOBILIZATION, CALCIFICATION OF RACHITIC BONE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4195027-A | Process for preparing 1α-hydroxylated compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-03-25 | — | — | US | disclosed |
| WO-1980000339-A1 | PROCESS FOR PREPARING 1-FLUORINATED VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RES FOUND (US) | 1980-03-06 | — | — | WO | disclosed |
| US-4189605-A | 3-Nitro-4-bromomethyl benzoic acid | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-02-19 | — | — | US | disclosed |
| US-4188345-A | FLUORINATION OF A 3,5-CYCLOVITAMIN D COMPOUND WITH A DIALKYLAMINO-SULFUR TRIFLUORIDE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1980-02-12 | — | — | US | disclosed |
| US-4172136-A | FOR URINARY TRACT INFECTIONS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-23 | — | — | US | disclosed |
| US-4157395-A | TREATMENT OF DIABETES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-05 | — | — | US | disclosed |
| US-4131674-A | TRANQUILIZERS, HYPNOTICS, ANTICONVULSANTS, ANTISPASMODICS | RHONE-POULENC INDUSTRIES (FR) | 1978-12-26 | — | — | US | disclosed |
| US-4108805-A | FIRE RETARDANT | ARMSTRONG CORK COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4105772-A | FOR URINARY TRACT INFECTIONS, BACTERICIDES | BOEHRINGER MANNHEIM GMBH (DE) | 1978-08-08 | — | — | US | disclosed |
| US-4086348-A | 2-(1,8-NAPHTHYRIDIN-2-YL)-3-AMINOCARBONYLOXYISOINOLIN-1-ONES; TRANQUILIZERS, HYPNOTICS, ANTICONVULSANTS, ANTISPASMODICS | RHONE-POULENC INDUSTRIES (FR) | 1978-04-25 | — | — | US | disclosed |
| US-4076658-A | BLOWING AGENT | ARMSTRONG CORK COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4055520-A | FIRE RETARDANT | ARMSTRONG CORK COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4053456-A | CROSSLINKING, SMOKELESS | ARMSTRONG CORK COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4008223-A | SPASMOLYTIC, ANTIPHLOGISTIC, TRANQUILIZER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-15 | — | — | US | disclosed |
| US-3987037-A | RADIATION-SENSITIVE FREE RADICAL GENERATORS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3984474-A | 4,5-Secoandrostanes | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3970641-A | Antibiotic 27,706 RP and salt thereof | RHONE-POULENC S.A. (FR) | 1976-07-20 | — | — | US | disclosed |
| US-3962244-A | LOWERING OF BLOOD-SUGAR LEVELS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3957766-A | BACTERIOSTATS, BACTERICIDES | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-05-18 | — | — | US | disclosed |
| US-3954475-A | Photosensitive elements containing chromophore-substituted vinyl-halomethyl-s-triazines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3939269-A | Benzenesulfon YL-semicarbazides for lowering blood sugar levels | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3939269-A | Benzenesulfon YL-semicarbazides for lowering blood sugar levels | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |