Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxane SCHEMBL10791372 | 1.00 | TTR (0.67) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dioxane SCHEMBL234551 | 1.00 | — | — | |
| Dioxane SCHEMBL11079749 | 0.95 | — | — | |
| Dioxane SCHEMBL11079311 | 0.95 | — | — | |
| Dioxane SCHEMBL11074566 | 0.95 | — | — | |
| Dioxane SCHEMBL11073120 | 0.95 | — | — | |
| Dioxane SCHEMBL3355965 | 0.95 | — | — | |
| Oxirane SCHEMBL844515 | 0.94 | — | — | |
| Dioxane SCHEMBL28216951 | 0.87 | ALDH1A1 (0.67) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| Dioxane SCHEMBL7807843 | 0.83 | ALDH1A1 (0.46) | TTRALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8007871-B2 | Electrospray deposition: devices and methods thereof | NANOSELECT, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-7696361-B2 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-04-13 | — | — | US | disclosed |
| US-20100068406-A1 | ELECTROSPRAY DEPOSITION: DEVICES AND METHODS THEREOF | NANOSELECT, INC. | 2010-03-18 | — | — | US | disclosed |
| WO-2007089650-A2 | ELECTROSPRAY DEPOSITION: DEVICES AND METHODS THEREOF | NANOSELECT, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20050010059-A1 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010059-A1 | Chemical reagents capable of selective attachment to and reaction with peptides and proteins | PTMS, FGB, DNPEP | TTR 426/4885ALDH1A1 4309/4885SMN1; SMN2 4205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.