SCHEMBL23458084

SCHEMBL23458084

Cc1ccc(CC(N)(CN)Cc2ccc(C)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
AGXT P21549 2/20 0.41
IDO1 P14902 3/20 0.41
ACHE P22303 2/20 0.40
SLC6A2 P23975 2/20 0.39
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
HRH1 P35367 1/20 0.39
HTR2B P41595 1/20 0.39
CHRNA4 P43681 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KIF11 P52732 2/20 0.39
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15362252 0.80 CYP1A2 (0.41) TAAR1CYP1A2CYP2A6AGXTIDO1
SCHEMBL7437594 0.80 TAAR1 (0.46) TAAR1CYP1A2CYP2A6AGXTIDO1
SCHEMBL8625798 0.79 ALDH1A1 (0.38) TAAR1CYP1A2CYP2A6SLC6A2HTR2A
SCHEMBL23458290 0.78 TSHR (0.43) TAAR1ACHESLC6A2HTR2ASLC6A4
SCHEMBL12063306 0.78 TAAR1 (0.48) TAAR1CYP1A2CYP2A6AGXTIDO1
SCHEMBL23458004 0.77 ALDH1A1 (0.50) SLC6A2HTR2ASLC6A4HRH1HTR2B
SCHEMBL23458259 0.77 IDO1 (0.47) IDO1SLC6A2HTR2ASLC6A4HRH1
SCHEMBL4433692 0.77 TAAR1 (0.53) TAAR1CYP1A2AGXTIDO1SLC6A4
SCHEMBL21410910 0.76 SLC6A2 (0.46) TAAR1CYP1A2CYP2A6AGXTIDO1
SCHEMBL10891421 0.76 SLC6A2 (0.64) TAAR1CYP1A2CYP2A6AGXTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069418-A1 PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST BASF SE (DE) 2022-10-12 EP disclosed
WO-2021110472-A1 PROCESS FOR PREPARING AMINES OVER A COPPER CATALYST BASF SE (DE) 2021-06-10 WO disclosed