Acridone

Acridone

SCHEMBL23458097

O=P(O)(O)OP(=O)(O)O.O=c1c2ccccc2[nH]c2ccccc12

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
KDM4E B2RXH2 4/20 0.67
GAA P10253 3/20 0.67
GLA P06280 2/20 0.67
HTT P42858 2/20 0.67
LMNA P02545 2/20 0.67
HPGD P15428 1/20 0.67
ATM Q13315 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
POLB P06746 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
CASP6 P55212 1/20 0.54
ABCG2 Q9UNQ0 3/20 0.50
NPC1 O15118 1/20 0.50
GPR3 P46089 2/20 0.46
HSD17B10 Q99714 2/20 0.46
PBRM1 Q86U86 1/20 0.46
IMPDH2 P12268 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridone SCHEMBL11519726 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL29641306 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL19289 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL29360611 0.82 ALDH1A1 (1.00) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL11523430 0.80 ALDH1A1 (0.95) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL28200023 0.80 ALDH1A1 (0.95) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL3420574 0.80 ALDH1A1 (0.95) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL27589416 0.80 ALDH1A1 (0.95) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL27512002 0.80 ALDH1A1 (0.95) ALDH1A1KDM4EGAAGLAHTT
Acridone SCHEMBL29395806 0.78 ALDH1A1 (0.82) ALDH1A1KDM4EGAAGLAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040324-A1 AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) 2023-02-09 US disclosed
EP-4069784-A1 AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-10-12 EP disclosed
WO-2021110280-A1 AMINOACRIDINE AND AMINOPYRENE DYES AND THEIR USE AS FLUORESCENT TAGS, IN PARTICULAR FOR CARBOHYDRATE ANALYSIS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) 2021-06-10 WO disclosed