Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23440270 | 0.84 | CYP2D6 (0.42) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL23440302 | 0.81 | CYP1A1 (0.40) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| Hydrochloric Acid SCHEMBL23458251 | 0.81 | PLAU (0.36) | ALDH1A1HPGDCNR2 | |
| SCHEMBL23480144 | 0.73 | CYP1A1 (0.43) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL23440307 | 0.70 | CYP1A1 (0.44) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL4038788 | 0.70 | STK17B (0.50) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL23440309 | 0.68 | CYP1A1 (0.42) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL5961133 | 0.68 | CA12 (0.44) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL5591652 | 0.67 | PLAU (0.54) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 | |
| SCHEMBL15084976 | 0.66 | MAOA (0.40) | CYP2D6CYP2C19CYP1A1CYP2B6CYP3A43 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230104758-A1 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | ETH ZURICH (CH) | 2023-04-06 | — | — | US | disclosed |
| WO-2021110834-A2 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | ETH ZURICH (CH) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230104758-A1 | COMPOUNDS AND METHODS FOR AMINE OXIDASE IMAGING | DAO, LOX, AOC2 | CYP2D6 494/4885CYP2C19 641/4885CYP1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.