SCHEMBL23458464

SCHEMBL23458464

c1ccc2c(-c3ccncc3)onc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 9/20 0.51
IP6K3 Q96PC2 7/20 0.51
IP6K2 Q9UHH9 7/20 0.51
ALDH1A1 P00352 9/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 4/20 0.45
KDM4E B2RXH2 3/20 0.45
NPC1 O15118 3/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
TP53 P04637 2/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 4/20 0.42
LMNA P02545 3/20 0.42
MAPK1 P28482 2/20 0.42
RAB9A P51151 2/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 2/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6691319 0.88 ALDH1A1 (0.55) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL2492556 0.86 ALDH1A1 (0.62) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL31001160 0.81 ALDH1A1 (0.46) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL10397089 0.79 ALDH1A1 (0.56) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL1837436 0.79 ALDH1A1 (0.47) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL8655645 0.79 MEN1 (0.56) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL28602742 0.79 ALDH1A1 (0.47) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL28526902 0.77 CYP2A6 (0.42) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL10395873 0.75 IP6K1 (0.47) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2
SCHEMBL10396913 0.75 IP6K1 (0.47) IP6K1IP6K3IP6K2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed