SCHEMBL23458474

SCHEMBL23458474

O=[N+]([O-])c1ccccc1C(O)c1ccncc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
ALDH1A1 P00352 7/20 0.45
TSHR P16473 1/20 0.44
MAPT P10636 1/20 0.39
CYP3A4 P08684 2/20 0.39
GPR35 Q9HC97 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
HSD17B10 Q99714 2/20 0.38
POLB P06746 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CDC7 O00311 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31633570 0.86 CYP1A2 (0.56) CYP1A2ALDH1A1TSHRMAPTCYP3A4
SCHEMBL5583438 0.86 CYP1A2 (0.56) CYP1A2ALDH1A1TSHRMAPTCYP3A4
SCHEMBL6940420 0.83 GAA (0.57) CYP1A2SMN1; SMN2GAAHTTALDH1A1
SCHEMBL506668 0.82 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL9489211 0.82 GAA (0.47) CYP1A2GAAALDH1A1TSHRMAPT
SCHEMBL5583370 0.77 ALDH1A1 (0.52) CYP1A2SMN1; SMN2GAAHTTALDH1A1
SCHEMBL13866738 0.77 CYP3A4 (0.47) CYP1A2SMN1; SMN2GAAHTTALDH1A1
SCHEMBL3697952 0.77 CYP1A2 (0.59) CYP1A2ALDH1A1TSHRCYP3A4GPR35
SCHEMBL17064547 0.75 ALDH1A1 (0.45) CYP1A2GAAALDH1A1TSHRMAPT
SCHEMBL4622229 0.75 ALDH1A1 (0.45) CYP1A2GAAALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed