⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770203 | 0.85 | SOS1 (0.48) | — | |
| SCHEMBL5358862 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL755085 | 0.79 | TAAR1 (0.59) | — | |
| SCHEMBL696776 | 0.77 | TAAR1 (0.56) | — | |
| SCHEMBL7545271 | 0.77 | TAAR1 (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL29222367 | 0.77 | TAAR1 (0.56) | — | |
| SCHEMBL15944871 | 0.75 | — | — | |
| SCHEMBL2932602 | 0.75 | — | — | |
| SCHEMBL15351724 | 0.75 | CYP1A2 (0.50) | — | |
| SCHEMBL16561361 | 0.73 | IDO1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307535-A | Compound containing acrylonitrile structure, application thereof and bactericide | 江苏中旗科技股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| WO-2024145659-A1 | HETEROCYCLE FUSED GAMMA-CARBOLINES ACTING ON THE SEROTONINE 5-HT2A RECEPTOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-20 | — | — | US | claimed |
| CN-115894486-B | Hydrogenated pyridoquinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| EP-4313943-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-02-07 | — | — | EP | claimed |
| CN-117043140-A | Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances | 拜耳公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115572278-B | Genipin derivative and preparation method and application thereof | 北京志道生物科技有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-112010844-B | Preparation method and application of N- (pyrimidine-2-yl) coumarin-7-amine derivative as protein kinase inhibitor | 中国药科大学 | 2023-07-25 | — | — | CN | claimed |
| WO-2023114313-A1 | PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | claimed |
| WO-2023080652-A1 | ANDROGEN RECEPTOR DEGRADERS FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER AND USE THEREOF | AUTOTAC INC. (KR) | 2023-05-11 | — | — | WO | claimed |
| EP-0183132-B1 | A PROCESS FOR THE PREPARATION OF HMG-COA REDUCTASE INHIBITORS AND INTERMEDIATE COMPOUNDS EMPLOYED THEREIN | MERCK FROSST CANADA INC. (CA) | 1989-10-18 | — | — | EP | claimed |
| US-4864035-A | Hydrogenation process for the formation of tetrahydro HMG-CoA reductase inhibitors | MERCK & CO., INC. (US) | 1989-09-05 | — | — | US | claimed |
| CN-86107695-A | The 3-piperidine carboxylic acid of different nitrogen-replacements or the 3-pyridine carboxylic acid of nitrogen-replacement and their derivative | — | 1987-05-13 | — | — | CN | claimed |
| US-4611068-A | Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein | MERCK FROSST CANADA, INC. (CA) | 1986-09-09 | — | — | US | claimed |
| US-4611067-A | VALEROLACTONE DERIVATIVES | MERCK & CO., INC. (US) | 1986-09-09 | — | — | US | claimed |
| US-4596822-A | Chromene or thiochromene ring containing enzyme inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1986-06-24 | — | — | US | claimed |
| EP-0183132-A2 | A process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein | MERCK FROSST CANADA INC. (CA) | 1986-06-04 | — | — | EP | claimed |
| US-4582914-A | STEREOSPECIFIC PREPARATION OF 3-HYDROXY-3-METHYLGLUTARYLCOENZYME A, A COMPACTIN AND MEVINOLIN DERIVATIVE | MERCK & CO., INC. (US) | 1986-04-15 | — | — | US | claimed |
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |