Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC2 | O75106 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755085 | 0.97 | TAAR1 (0.59) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5785 | 0.90 | MAOB (0.61) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL386493 | 0.84 | TAAR1 (0.52) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL9047472 | 0.82 | TAAR1 (0.50) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL7437052 | 0.82 | TAAR1 (0.68) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL10685072 | 0.82 | ALDH1A1 (0.69) | TAAR1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL8588226 | 0.80 | TAAR1 (0.48) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL9335133 | 0.80 | TAAR1 (0.48) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL696776 | 0.78 | TAAR1 (0.56) | TAAR1MAOBIDO1LOXL2AOC3 | |
| SCHEMBL23461 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482990-B1 | Prostaglandin E analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1211241-A1 | PROSTAGLANDIN E ANALOGUES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-06-05 | — | — | EP | disclosed |