Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170826 | 0.87 | GPR35 (0.49) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL1736274 | 0.87 | POLB (0.52) | GPR35SNCAMAPTHPGDALDH1A1 | |
| SCHEMBL11247481 | 0.84 | CYP3A4 (0.50) | MAPTALDH1A1CYP3A4LMNATDP1 | |
| SCHEMBL10819595 | 0.83 | GPR35 (0.47) | GPR35SNCASIRT6MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11339240 | 0.82 | IDO1 (0.56) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL4962677 | 0.81 | GPR35 (0.56) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL27671999 | 0.81 | GPR35 (0.49) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL28917367 | 0.81 | GPR35 (0.49) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL9198508 | 0.80 | SNCA (0.62) | GPR35SNCASIRT6MAPTHPGD | |
| SCHEMBL31449975 | 0.80 | CYP19A1 (0.40) | MAPTALDH1A1CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222381-B2 | Derivatives of monosaccharides for drug discovery | ALCHEMIA LIMITED (AU) | 2012-07-17 | — | — | US | disclosed |
| EP-1646606-B1 | 2-AMINO-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | PROCTER & GAMBLE (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7226487-B2 | Oxidative dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| US-7226487-B2 | Oxidative dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| US-7226487-B2 | Oxidative dyeing keratin fibers | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| CN-1819989-A | 2-(amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2006-08-16 | — | — | CN | disclosed |
| EP-1646606-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007615-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5-(SUBSTITUTED OXYMETHYL)-PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-27 | — | — | WO | disclosed |
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050005370-A1 | 2-(Amino or substituted amino)-5-(substituted oxymethyl)-phenol compounds, dyeing compositions containing them, and use thereof | KRT18, LOX, TYR | GPR35 1851/4885SNCA 3236/4885SIRT6 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.